[达拉argin对应激大鼠血液中内啡肽、亮氨酸脑啡肽、促肾上腺皮质激素和皮质酮含量的影响]
[Effect of dalargin on the content of endorphins, leucine-enkephalin ACTH and corticosterone of the blood of stressed rats].
作者信息
Bobkov A I, Polonskiĭ V M, Vinogradov V A, Demina D G, Smagin V G
出版信息
Biull Eksp Biol Med. 1985 Dec;100(12):715-7.
PMID:3000473
Abstract
Stress caused by acute cysteamine duodenal ulcer was induced in Wistar male rats. All the endogenous opioides under study were involved in the stress-reaction mechanism. Protective dalargin (synthetic enkephalin analogue) administration revealed a tendency towards normalization of endorphin, L-enkephalin and ACTH blood levels.
摘要
通过向雄性Wistar大鼠十二指肠注射半胱胺诱导出急性应激性溃疡。所有研究的内源性阿片样物质均参与应激反应机制。给予具有保护作用的达乐精（一种合成脑啡肽类似物）后，内啡肽、亮氨酸脑啡肽和促肾上腺皮质激素的血药浓度有恢复正常的趋势。
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