Hofmann Elisabeth, Detterbeck Andreas, Chepura Taras, Kirschneck Christian, Schmid Matthias, Hirschfelder Ursula
Department of Orthodontics and Orofacial Orthopedics, Friedrich-Alexander University Erlangen-Nuernberg, Erlangen, Germany.
Department of Orthodontics, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany.
J Orofac Orthop. 2018 Jul;79(4):259-266. doi: 10.1007/s00056-018-0141-5. Epub 2018 Jun 8.
To evaluate, by comparing maxillary sinus volumes, how asymmetries related to oculoauriculovertebral spectrum (OAVS) affect upper-jaw development.
From pre-existing multislice spiral computed tomography (MSCT) datasets, we selected 20 cases of 11 female and 9 male patients aged 6.1-24 years who were clinically and radiographically symmetrical (group 1) plus 20 cases of 8 female and 12 male patients aged 5.7-23.9 years who had OAVS (group 2). After three-dimensional reconstruction of the datasets, the volumes of the left and right maxillary sinuses were calculated and compared based on patient groups and based on the sides affected or unaffected by OAVS. To this end, the OAVS patients were subdivided into a group in whom both external acoustic pores were radiographically present (group 2a) and a group in whom the pore on the affected side was congenitally missing (group 2b).
Intrarater reliability was very high (0.997). Significantly larger volumes of the maxillary sinuses, amounting to a mean of 13.4 ml, were observed in the control group than in the asymmetric OAVS groups where the volumes averaged 9.8 ml or 10.3 ml, respectively (p = 0.03). No statistically significant differences in sinus volumes were found between the two OAVS groups (p = 0.557) and between the sides affected or unaffected by the OAVS (p = 0.8311 in group 2a and 0.4961 in group 2b).
Overall, we found the volumes of both maxillary sinuses to be somewhat smaller in the asymmetric patients than in the symmetric control group. This might indicate that OAVS was associated with a mild generalized hypoplasia of the maxilla, but significantly different sinus volumes were not seen between the affected and unaffected sides.
通过比较上颌窦容积，评估与眼耳脊椎综合征（OAVS）相关的不对称性如何影响上颌骨发育。
从现有的多层螺旋计算机断层扫描（MSCT）数据集中，我们选取了20例年龄在6.1至24岁之间的患者，其中11例女性，9例男性，这些患者在临床和影像学上均表现对称（第1组），另外选取了20例年龄在5.7至23.9岁之间的患者，其中8例女性，12例男性，这些患者患有OAVS（第2组）。在对数据集进行三维重建后，根据患者分组以及受OAVS影响或未受影响的侧别，计算并比较左右上颌窦的容积。为此，将患有OAVS的患者细分为两组，一组是两侧外耳道在影像学上均存在（第2a组），另一组是患侧外耳道先天性缺失（第2b组）。
同一评估者的可靠性非常高（0.997）。与不对称的OAVS组相比，对照组中观察到上颌窦容积明显更大，对照组平均为13.4毫升，而OAVS组的容积分别平均为9.8毫升或10.3毫升（p = 0.03）。在两个OAVS组之间（p = 0.557）以及受OAVS影响或未受影响的侧别之间（第2a组中p = 0.8311，第2b组中p = 0.4961），未发现窦腔容积有统计学上的显著差异。
总体而言，我们发现不对称患者的双侧上颌窦容积比对称对照组略小。这可能表明OAVS与上颌骨轻度普遍性发育不全有关，但患侧和未患侧之间未观察到明显不同的窦腔容积。
