Tanaka Midori, Sugawara Motoaki, Niki Kiyomi, Ogasawara Yasuo
Faculty of Health Care Sciences, Himeji Dokkyo University, 7-2-1 Kamiohno, Himeji, 670-8524, Japan.
Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.
J Med Ultrason (2001). 2019 Jan;46(1):63-68. doi: 10.1007/s10396-018-0888-8. Epub 2018 Jun 15.
Estimation of the contractility of the left ventricle during exercise is an important part of the rehabilitation protocol. It is known that cardiac contractility increases with an increase in heart rate. This phenomenon is called the force-frequency relation (FFR). Using wave intensity, we aimed to evaluate FFR noninvasively during graded exercise.
We enrolled 83 healthy subjects. Using ultrasonic diagnostic equipment, we measured wave intensity (WD), which was defined in terms of blood velocity and arterial diameter, in the carotid artery and heart rate (HR) before and during bicycle ergometer exercise. FFRs were constructed by plotting the maximum value of WD (WD) against HR. We analyzed the variation among FFR responses of individual subjects.
WD increased linearly with an increase in HR during exercise. The average slope of the FFR was 1.0 ± 0.5 m/s bpm. The slope of FFR decreased with an increase in body mass index (BMI). The slopes of FFRs were steeper in men than women, although there were no differences in BMI between men and women.
The FFR was obtained noninvasively by carotid arterial wave intensity (WD) and graded exercise. The slope of the FFR decreased with an increase in BMI, and was steeper in men than women.
评估运动期间左心室的收缩性是康复方案的重要组成部分。众所周知，心脏收缩性随心率增加而增强。这种现象称为力-频率关系（FFR）。我们旨在通过波强度在分级运动期间无创评估FFR。
我们招募了83名健康受试者。使用超声诊断设备，我们在自行车测力计运动前和运动期间测量了颈动脉处的波强度（WD，根据血流速度和动脉直径定义）以及心率（HR）。通过绘制WD的最大值（WD）与HR的关系构建FFR。我们分析了个体受试者FFR反应之间的差异。
运动期间WD随HR增加呈线性增加。FFR的平均斜率为1.0±0.5 m/s bpm。FFR的斜率随体重指数（BMI）增加而降低。FFR的斜率男性比女性更陡，尽管男性和女性的BMI没有差异。
通过颈动脉波强度（WD）和分级运动无创获得FFR。FFR的斜率随BMI增加而降低，且男性比女性更陡。
