Kamper L, Dreger N M, Brandt A S, Pöppel T, Abanador-Kamper N, Roth S, Haage P
Radiology, HELIOS University Hospital Wuppertal, University Witten/Herdecke, Heusnerstr. 40, 42283, Wuppertal, Germany.
Urology, HELIOS University Hospital Wuppertal, University Witten/Herdecke, Heusnerstr. 40, 42283, Wuppertal, Germany.
Int J Cardiovasc Imaging. 2018 Nov;34(11):1779-1785. doi: 10.1007/s10554-018-1395-0. Epub 2018 Jun 15.
Aim of the present study is to compare magnetic resonance imaging (MRI) and positron emission tomography (PET) parameters in the follow up of chronic periaortitis (CP), with a focus on changes in the apparent diffusion coefficient (ADC) and standardized uptake values (SUV). 127 patients with CP were treated in our urology between 2007 and 2017. We identified 14 patients with parallel abdominal MRI and PET-CT examinations before therapy and in the follow up resulting in a total of 56 examinations. Relative contrast uptake and diffusion-weighted MRI parameters were compared to SUV in the corresponding PET-CT examinationsand laboratory infection markers. All examined MRI and PET-CT parameters showed significant changes between basis and follow-up examinations. Median ADC values increased significantly (p < 0.001) in the follow up. SUVmax and the other MR parameter (contrast uptake, DWI-signal) declined significantly. We observed a strong negative correlation between ADC and SUVmax (rho: - 0.61; p < 0.001). In addition, we found an inverse correlation of ADC with the inflammation markers ESR (rho: - 0.64; p < 0.001) and CRP (rho: - 0.54; p = 0.001). MRI and PET-CT showed comparable results in the individual follow up of CP and compared to laboratory inflammation markers. Our data support MRI as first imaging modality due to absent radiation and the necessity of repetitive follow-up examinations in patients with CP.
本研究的目的是比较慢性主动脉周炎（CP）随访中磁共振成像（MRI）和正电子发射断层扫描（PET）参数，重点关注表观扩散系数（ADC）和标准化摄取值（SUV）的变化。2007年至2017年间，我们泌尿外科共治疗了127例CP患者。我们确定了14例在治疗前及随访期间同时进行腹部MRI和PET-CT检查的患者，共计56次检查。将相对对比剂摄取和扩散加权MRI参数与相应PET-CT检查中的SUV及实验室感染标志物进行比较。所有检查的MRI和PET-CT参数在基线检查和随访检查之间均显示出显著变化。随访期间，ADC值中位数显著增加（p < 0.001）。SUVmax及其他MR参数（对比剂摄取、DWI信号）显著下降。我们观察到ADC与SUVmax之间存在强负相关（rho：-0.61；p < 0.001）。此外，我们发现ADC与炎症标志物血沉（ESR）（rho：-0.64；p < 0.001）和C反应蛋白（CRP）（rho：-0.54；p = 0.001）呈负相关。在CP的个体随访中，MRI和PET-CT显示出可比的结果，且与实验室炎症标志物相比也是如此。由于无辐射以及CP患者需要重复进行随访检查，我们的数据支持将MRI作为首选成像方式。
