Doi Shogo, Kuroiwa Yasuyoshi, Kusumoto Kazunori, Yamashita Atsushi, Furukoji Eiji, Tai Hiroshi, Kihara Yasushi, Hirai Toshinori, Asada Yujiro, Imamura Takuroh
Department of Radiological Technology, Koga General Hospital, Miyazaki, Japan.
Department of Pathology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan.
Radiol Case Rep. 2019 Jul 16;14(9):1132-1135. doi: 10.1016/j.radcr.2019.06.020. eCollection 2019 Sep.
Immunoglobulin (IgG) 4-related disease is a systemic inflammatory disease, and it affects vascular system as aortitis, periaortitis, or aneurysm. However, due to a lack of serum biomarker on aortic damage and the multiorgan involvement, it is difficult to assess aortic inflammatory activity of IgG4-related disease. We described a case of IgG4-related pancreatitis and aortitis, which was visualized with magnetic resonance merged image of diffusion weighted and T weighted images. The aortic signal intensity or apparent diffusion coefficient value reduced or increased after oral prednisone administration, respectively. Magnetic resonance diffusion weighted image and apparent diffusion coefficient may be a useful imaging tool for assessment of vascular inflammation in IgG4-related aortitis.
免疫球蛋白（IgG）4相关疾病是一种全身性炎症性疾病，它可作为主动脉炎、主动脉周炎或动脉瘤影响血管系统。然而，由于缺乏主动脉损伤的血清生物标志物以及多器官受累，难以评估IgG4相关疾病的主动脉炎症活动。我们描述了一例IgG4相关胰腺炎和主动脉炎病例，通过扩散加权成像与T加权成像的磁共振融合图像对其进行了可视化。口服泼尼松后，主动脉信号强度或表观扩散系数值分别降低或升高。磁共振扩散加权成像和表观扩散系数可能是评估IgG4相关主动脉炎血管炎症的有用成像工具。
