Gong W, Liang L, Zheng D G, Zhong R S, Zhu Y X, Wen Y J
Clin Exp Obstet Gynecol. 2017;44(3):496-498.
Fetal immature mediastinal teratoma is a rare disease. The pressure generated by the tumor mass can cause hydrops fetalis, pulmonary hypoplasia, pleural and peritoneal effusion, and polyhydramnios which cause the death of the fetus. Routine prenatal ultrasound has enabled accurate diagnosis.
The authors report a 26-year-old patient, gravida 4 para 1, who was referred to this hospital, carrying a fetus with immature mediastinal teratoma.
At 27 weeks of gestation, a routine prenatal ultrasound suggested the fetus had a mass at the anterior mediastinum, accompanied by pulmonary hypoplasia, pleural and peritoneal effusion, subcutaneous edema of head and chest, and polyhydramnios. After the therapeutic abortion, the gross anatomy confirmed the mediastinal mass. The histological examination showed that the mass was a grade 2 immature teratoma.
The mother of the fetus had been exposed to plaster, paint, and paint-thinner in the first trimester of pregnancy, suggesting that these chemical contacts may be one of the causes of the disorder.
胎儿未成熟纵隔畸胎瘤是一种罕见疾病。肿瘤团块产生的压力可导致胎儿水肿、肺发育不全、胸腔和腹腔积液以及羊水过多，从而导致胎儿死亡。常规产前超声已能实现准确诊断。
作者报告了一名26岁、孕4产1的患者，该患者转诊至本院，其胎儿患有未成熟纵隔畸胎瘤。
妊娠27周时，常规产前超声提示胎儿前纵隔有一肿块，伴有肺发育不全、胸腔和腹腔积液、头部和胸部皮下水肿以及羊水过多。治疗性流产后，大体解剖证实为纵隔肿块。组织学检查显示该肿块为2级未成熟畸胎瘤。
胎儿的母亲在妊娠早期接触过石膏、油漆和稀释剂，提示这些化学接触可能是该病症的病因之一。
