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强迫症患者的劳动力市场边缘化:一项全国范围内基于登记册的同胞对照研究。

Labour market marginalisation in obsessive-compulsive disorder: a nationwide register-based sibling control study.

机构信息

Department of Clinical Neuroscience, Centre forPsychiatry Research,Karolinska Institutet,Stockholm,Sweden.

Division of Insurance Medicine,Department of Clinical Neuroscience,Karolinska Institutet,Stockholm,Sweden.

出版信息

Psychol Med. 2019 Apr;49(6):1015-1024. doi: 10.1017/S0033291718001691. Epub 2018 Jun 28.

Abstract

BACKGROUND

The impact of obsessive-compulsive disorder (OCD) on objective indicators of labour market marginalisation has not been quantified.

METHODS

Linking various Swedish national registers, we estimated the risk of three labour market marginalisation outcomes (receipt of newly granted disability pension, long-term sickness absence and long-term unemployment) in individuals diagnosed with OCD between 2001 and 2013 who were between 16 and 64 years old at the date of the first OCD diagnosis (n = 16 267), compared with matched general population controls (n = 157 176). Hazard ratios (HR) with 95% confidence intervals (CI) were calculated using Cox regression models, adjusting for a number of covariates (e.g. somatic disorders) and stratifying by sex. To adjust for potential familial confounders, we further analysed data from 7905 families that included full siblings discordant for OCD.

RESULTS

Patients were more likely to receive at least one outcome of interest [adjusted HR = 3.63 (95% CI 3.53-3.74)], including disability pension [adjusted HR = 16.36 (95% CI 15.34-17.45)], being on long-term sickness absence [adjusted HR = 3.07 (95% CI 2.95-3.19)] and being on long-term unemployment [adjusted HR = 1.72 (95% CI 1.63-1.82)]. Results remained similar in the adjusted sibling comparison models. Exclusion of comorbid psychiatric disorders had a minimal impact on the results.

CONCLUSIONS

Help-seeking individuals with OCD diagnosed in specialist care experience marked difficulties to participate in the labour market. The findings emphasise the need for cooperation between policy-makers, vocational rehabilitation and mental health services in order to design and implement specific strategies aimed at improving the patients' participation in the labour market.

摘要

背景

强迫症 (OCD) 对劳动力市场边缘化的客观指标的影响尚未量化。

方法

通过链接各种瑞典国家登记处,我们估计了 2001 年至 2013 年间被诊断患有 OCD 的年龄在 16 至 64 岁之间的个体(n = 16267)的三种劳动力市场边缘化结果(新获得残疾抚恤金、长期病假和长期失业)的风险,与匹配的一般人群对照(n = 157176)。使用 Cox 回归模型计算风险比(HR)和 95%置信区间(CI),并调整了一些协变量(例如躯体疾病),按性别分层。为了调整潜在的家族混杂因素,我们进一步分析了包括全同胞 OCD 不一致的 7905 个家庭的数据。

结果

患者更有可能出现至少一种感兴趣的结果[调整后的 HR = 3.63(95%CI 3.53-3.74)],包括残疾抚恤金[调整后的 HR = 16.36(95%CI 15.34-17.45)]、长期病假[调整后的 HR = 3.07(95%CI 2.95-3.19)]和长期失业[调整后的 HR = 1.72(95%CI 1.63-1.82)]。在调整后的同胞比较模型中,结果仍然相似。排除共患精神障碍对结果的影响很小。

结论

在专科护理中寻求帮助的 OCD 患者在参与劳动力市场方面遇到了明显的困难。这些发现强调了政策制定者、职业康复和精神卫生服务之间需要合作,以制定和实施旨在改善患者参与劳动力市场的具体策略。

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