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Ann Transl Med. 2018 May;6(10):186. doi: 10.21037/atm.2018.03.06.
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1
Amylase, Lipase, and Acute Pancreatitis in People With Type 2 Diabetes Treated With Liraglutide: Results From the LEADER Randomized Trial.利拉鲁肽治疗 2 型糖尿病患者的淀粉酶、脂肪酶和急性胰腺炎：来自 LEADER 随机试验的结果。
Diabetes Care. 2017 Jul;40(7):966-972. doi: 10.2337/dc16-2747. Epub 2017 May 5.
2
Safety issues with glucagon-like peptide-1 receptor agonists (pancreatitis, pancreatic cancer and cholelithiasis): Data from randomized controlled trials.胰高血糖素样肽-1 受体激动剂（胰腺炎、胰腺癌和胆石症）的安全性问题：来自随机对照试验的数据。
Diabetes Obes Metab. 2017 Sep;19(9):1233-1241. doi: 10.1111/dom.12926. Epub 2017 Jun 20.
3
3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial.利拉鲁肽治疗 3 年对糖尿病前期个体的 2 型糖尿病风险降低和体重管理的效果：一项随机、双盲试验。
Lancet. 2017 Apr 8;389(10077):1399-1409. doi: 10.1016/S0140-6736(17)30069-7. Epub 2017 Feb 23.
4
Glucagon-like peptide-1 receptor agonists and risk of acute pancreatitis in patients with type 2 diabetes.胰高血糖素样肽-1 受体激动剂与 2 型糖尿病患者急性胰腺炎风险的关系。
Diabetes Obes Metab. 2017 Jun;19(6):906-908. doi: 10.1111/dom.12885. Epub 2017 Mar 17.
5
Incretin-Based Therapy and Risk of Pancreatic Cancer in Patients with Type 2 Diabetes Mellitus: A Meta-analysis of Randomized Controlled Trials.基于肠促胰岛素的疗法与2型糖尿病患者患胰腺癌的风险：一项随机对照试验的荟萃分析
Diabetes Ther. 2016 Dec;7(4):725-742. doi: 10.1007/s13300-016-0198-3. Epub 2016 Sep 21.
6
Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes.利拉鲁肽与2型糖尿病患者的心血管结局
N Engl J Med. 2016 Jul 28;375(4):311-22. doi: 10.1056/NEJMoa1603827. Epub 2016 Jun 13.
7
Incretin based drugs and the risk of pancreatic cancer: international multicentre cohort study.基于肠促胰岛素的药物与胰腺癌风险：国际多中心队列研究
BMJ. 2016 Feb 17;352:i581. doi: 10.1136/bmj.i581.
8
A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management.利拉鲁肽 3.0 毫克在体重管理中的随机、对照试验。
N Engl J Med. 2015 Jul 2;373(1):11-22. doi: 10.1056/NEJMoa1411892.
9
The Effect of Glucagon-Like Peptide 1 Receptor Agonists on Weight Loss in Type 2 Diabetes: A Systematic Review and Mixed Treatment Comparison Meta-Analysis.胰高血糖素样肽-1受体激动剂对2型糖尿病患者体重减轻的影响：一项系统评价与混合治疗比较的Meta分析
PLoS One. 2015 Jun 29;10(6):e0126769. doi: 10.1371/journal.pone.0126769. eCollection 2015.
10
Incretin-based drugs and adverse pancreatic events: almost a decade later and uncertainty remains.基于肠降血糖素的药物与胰腺不良事件：近十年后，不确定性依然存在。
Diabetes Care. 2015 Jun;38(6):951-3. doi: 10.2337/dc15-0347.

Can we exonerate GLP-1 receptor agonists from blame for adverse pancreatic events?

作者信息

Murphy Conor F, le Roux Carel W

机构信息

Diabetes Complications Research Centre, Conway Institute, University College Dublin, Dublin, Ireland.

Gastrosurgical laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

出版信息

Ann Transl Med. 2018 May;6(10):186. doi: 10.21037/atm.2018.03.06.

DOI:10.21037/atm.2018.03.06
PMID:29951508
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5994527/
Abstract
摘要