Tog C, Liu D S, Lim H K, Stiven P, Thompson S K, Watson D I, Aly A
Department of Surgery Austin Hospital Heidelberg Victoria Australia.
Division of Cancer Surgery Peter MacCallum Cancer Centre Melbourne Victoria Australia.
BJS Open. 2017 Aug 28;1(3):75-83. doi: 10.1002/bjs5.11. eCollection 2017 Jun.
Delayed gastric emptying can complicate surgery for hiatus hernia. The aim of this study was to quantify its incidence following laparoscopic repair of very large hiatus hernias, identify key risk factors for its occurrence and determine its impact on clinical outcomes.
Data collected from a randomized trial of patients who underwent laparoscopic mesh versus sutured repair of very large hiatus hernias (more than 50 per cent of stomach in chest) were analysed retrospectively. Delayed gastric emptying was defined as endoscopic evidence of solid food in the stomach after fasting for 6 h at 6 months after surgery.
Delayed gastric emptying occurred in 19 of 102 patients (18·6 per cent). In univariable analysis, type 2 paraoesophageal hernia (relative risk (RR) 3·15, 95 per cent c.i. 1·41 to 7·06), concurrent anterior and posterior hiatal repair (RR 2·66, 1·14 to 6·18), hernia sac excision (RR 4·85, 1·65 to 14·24), 270°/360° fundoplication (RR 3·64, 1·72 to 7·68), division of short gastric vessels (RR 6·82, 2·12 to 21·90) and revisional surgery (RR 3·69, 1·73 to 7·87) correlated with delayed gastric emptying. In multivariable analysis, division of short gastric vessels (RR 6·27, 1·85 to 21·26) and revisional surgery (RR 6·19, 1·32 to 28·96) were independently associated with delayed gastric emptying. Delayed gastric emptying correlated with adverse gastrointestinal symptomatology, including higher rates of bloating, nausea, vomiting and anorexia, as well as reduced patient satisfaction with the operation and recovery.
Delayed gastric emptying following large hiatus hernia repair is common and associated with adverse symptoms and reduced patient satisfaction. Division of short gastric vessels and revisional surgery were independently associated with its occurrence.
胃排空延迟会使食管裂孔疝手术变得复杂。本研究的目的是量化腹腔镜修复巨大食管裂孔疝后胃排空延迟的发生率,确定其发生的关键危险因素,并确定其对临床结局的影响。
回顾性分析从一项针对接受腹腔镜补片与缝合修复巨大食管裂孔疝(胸腔内胃占比超过50%)患者的随机试验中收集的数据。胃排空延迟定义为术后6个月禁食6小时后胃内存在固体食物的内镜证据。
102例患者中有19例(18.6%)发生胃排空延迟。单因素分析中,2型食管旁疝(相对危险度(RR)3.15,95%可信区间1.41至7.06)、同时进行前后裂孔修复(RR 2.66,1.14至6.18)、疝囊切除(RR 4.85,1.65至14.24)、270°/360°胃底折叠术(RR 3.64,1.72至7.68)、切断胃短血管(RR 6.82,2.12至21.90)和再次手术(RR 3.69,1.73至7.87)与胃排空延迟相关。多因素分析中,切断胃短血管(RR 6.27,1.85至21.26)和再次手术(RR 6.19,1.32至28.96)与胃排空延迟独立相关。胃排空延迟与不良胃肠道症状相关,包括腹胀、恶心、呕吐和厌食发生率较高,以及患者对手术和恢复的满意度降低。
巨大食管裂孔疝修复术后胃排空延迟很常见,且与不良症状和患者满意度降低相关。切断胃短血管和再次手术与胃排空延迟的发生独立相关。