Siddiqi Najam, Valdevit Antonio, Chao E Y S
Biomechanics Laboratory, School of Medicine, Johns Hopkins University, 720 Rutland Avenue, Baltimore, MD, 21205, USA.
Department of Anatomy, National University of Science and Technology, College of Medicine and Health Sciences, Al-Tareef, PO Box 391, Zip Code: 321, Sohar, Sultanate of Oman.
Anat Sci Int. 2019 Jan;94(1):58-66. doi: 10.1007/s12565-018-0450-1. Epub 2018 Jun 27.
The purpose of this study was to identify the differences in femoral dimensions among Caucasian and Oriental populations. A total of 268 femora were collected from China, Japan, Korea, Taiwan and the United States. Firstly, the dimensional parameters for measuring femur were identified. These were initially measured on bone specimens to determine the methodology, followed by measuring the same parameter on plane radiographs of the same bone specimen using a board, and digitized with the aim of verifying the repeatability and reliability of the data. Data were analyzed using ANOVA, paired students t test and Pearson's correlation analysis. The results revealed that Caucasian femora are significantly larger in maximum bone length (BL), head-neck length (HNL), lesser trochanter width and the total width of the distal epiphysis (Wdf). The Beijing femora were found to be the longest and the Japanese femora constituted the shortest bone lengths and smallest angle alpha among the Oriental populations. A strong correlation was observed between Wdf and HD, HNL, Wmc and Wlc in all the populations; however, correlation between Wdf and BL was mild. The angle alpha showed no correlation with BL. This study generated a large database of femoral geometry, which may help pharmaceutical companies to design orthopedic implants for Oriental populations.
本研究的目的是确定白种人和东方人群股骨尺寸的差异。共收集了来自中国、日本、韩国、台湾和美国的268根股骨。首先，确定了测量股骨的尺寸参数。这些参数最初在骨标本上测量以确定方法，随后使用模板在同一骨标本的平面X线片上测量相同参数，并进行数字化处理，目的是验证数据的可重复性和可靠性。使用方差分析、配对学生t检验和皮尔逊相关分析对数据进行分析。结果显示，白种人的股骨在最大骨长（BL）、头颈长（HNL）、小转子宽度和远端骨骺总宽度（Wdf）方面明显更大。在东方人群中，北京人的股骨最长，日本人的股骨长度最短且α角最小。在所有人群中，均观察到Wdf与HD、HNL、Wmc和Wlc之间存在强相关性；然而，Wdf与BL之间的相关性较弱。α角与BL无相关性。本研究生成了一个庞大的股骨几何数据库，这可能有助于制药公司为东方人群设计骨科植入物。
