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腹腔镜胃大弯折叠术和腹腔镜袖状胃切除术治疗肥胖症:短期和中期结果的系统评价和荟萃分析。

Laparoscopic Greater Curvature Plication and Laparoscopic Sleeve Gastrectomy Treatments for Obesity: Systematic Review and Meta-Analysis of Short- and Mid-Term Results.

机构信息

Gastrointestinal Endoscopy Unit, Gastroenterology Department, University of São Paulo, CEP, São Paulo, SP, 05403-900, Brazil.

Servei de Cirurgia General i de l'Aparell Digestiu, Hospital Universitari de Bellvitge, Barcelona, Spain.

出版信息

Obes Surg. 2018 Oct;28(10):3199-3212. doi: 10.1007/s11695-018-3330-9.

DOI:10.1007/s11695-018-3330-9
PMID:29951784
Abstract

BACKGROUND

Laparoscopic greater curvature plication (LGP) has recently emerged as a new bariatric procedure. This surgery provides gastric restriction without resection, which could potentially provide a lower risk alternative, with fewer complications. The real benefit of this technique in the short and long term is unknown. This systematic review aims to compare laparoscopic gastric plication and laparoscopic sleeve gastrectomy for obesity treatment.

METHODS

Clinical trials were identified in MEDLINE, Embase, Cochrane, LILACS, BVS, SCOPUS, and CINAHL databases. Comparison of LGP and laparoscopic sleeve gastrectomy (SG) included hospital stay, operative time, loss of hunger feeling, body mass index loss (BMIL), percentage of excess weight loss (%EWL), complications, symptoms in the postoperative period, and comorbidity remission or improvement.

RESULTS

This systematic review search included 17,423 records. Eight studies were selected for meta-analysis. There is no difference in operative time, hospital stay, and complications. Patients in the SG group had improved loss of hunger feeling. BMIL was better in the SG group at 12 and 24 months [mean difference (MD) - 2.19, 95% confidence interval (CI) - 3.10 to - 1.28, and MD - 4.59, 95% CI - 5.55 to - 3.63, respectively]. SG showed improved %EWL compared with gastric plication in 3, 6, 12, and 24 months. However, no difference was found in %EWL long-term results (24 and 36 months). Patients who underwent LGP had more sialorrhea. SG showed better results in diabetes remission.

CONCLUSIONS

SG showed improved weight loss when compared with LGP, with better satiety, fewer symptoms in the postoperative period, and improved diabetes remission.

摘要

背景

腹腔镜胃大弯折叠术(LGP)最近作为一种新的减重手术出现。这种手术提供胃限制而不切除,这可能提供一种风险较低的替代方案,并发症较少。这种技术的短期和长期真正益处尚不清楚。本系统评价旨在比较腹腔镜胃折叠术和腹腔镜袖状胃切除术治疗肥胖症。

方法

在 MEDLINE、Embase、Cochrane、LILACS、BVS、SCOPUS 和 CINAHL 数据库中确定临床试验。LGP 与腹腔镜袖状胃切除术(SG)的比较包括住院时间、手术时间、饥饿感丧失、体重指数损失(BMIL)、多余体重减轻百分比(%EWL)、并发症、术后症状以及合并症缓解或改善。

结果

本系统评价搜索包括 17423 条记录。选择了八项研究进行荟萃分析。手术时间、住院时间和并发症没有差异。SG 组患者的饥饿感改善。SG 组在 12 和 24 个月时 BMIL 更好[平均差值(MD)-2.19,95%置信区间(CI)-3.10 至-1.28,和 MD-4.59,95%CI-5.55 至-3.63]。SG 在 3、6、12 和 24 个月时与胃折叠术相比,%EWL 有所改善。然而,在 24 和 36 个月的长期结果中,%EWL 没有差异。行 LGP 的患者唾液分泌更多。SG 在糖尿病缓解方面表现更好。

结论

与 LGP 相比,SG 显示出更好的减重效果,具有更好的饱腹感、术后症状更少、糖尿病缓解改善。

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