Zhang Mei-Jia, Mu Ji-Wei, Chen Xiang-Ru, Zhang Xin, Feng Chong
Department of Otolaryngology, First Affiliated Hospital of Jiamusi University, Jiamusi Department of Ultrasound, Second Affiliated Hospital of Mudanjiang Medical University Department of Ultrasound, Hongqi Affiliated Hospital of Mudanjiang Medical University, Mudanjiang, China.
Medicine (Baltimore). 2018 Jun;97(26):e11268. doi: 10.1097/MD.0000000000011268.
This retrospective study examined the effect of voice rehabilitation training (VRT) for patients with laryngeal cancer (LC) after radiotherapy.Eighty-three eligible patients with LC were included. Forty-three patients were assigned to a treatment group, and underwent VRT, while the other 40 subjects were assigned to a control group, and were at waiting list. Primary outcome was measured by the Grade, Roughness, Breathiness, Asthenia, and Strain (GRBAS) scale. Secondary outcome was measured by Patient Perception Measures. All outcomes were measured before and 3 months after VRT intervention.Patients in the treatment group did not show better outcomes, measured by GRBAS scale (Grade, P = .78; Roughness, P = .61; Breathiness, P = .83; Ashenia, P = .89; and Strain, P = .41), and Patient Perception Measures (Vocal quality, P = .17; Acceptability, P = .35; Hoarseness, P = .23; Vocal fatigue, P = .39; and Ashamed, P = .51), compared with patients in the control group.The results of this study did not exert better outcomes in patients received VRT than those at waiting list.
这项回顾性研究探讨了放疗后喉癌(LC)患者进行嗓音康复训练(VRT)的效果。纳入了83例符合条件的LC患者。43例患者被分配到治疗组并接受VRT,而其他40例受试者被分配到对照组并处于等待名单中。主要结局通过等级、粗糙度、气息声、无力和紧张(GRBAS)量表进行测量。次要结局通过患者感知指标进行测量。所有结局均在VRT干预前和干预后3个月进行测量。通过GRBAS量表(等级,P = 0.78;粗糙度,P = 0.61;气息声,P = 0.83;无力,P = 0.89;紧张,P = 0.41)和患者感知指标(嗓音质量,P = 0.17;可接受性,P = 0.35;嘶哑,P = 0.23;嗓音疲劳,P = 0.39;羞愧,P = 0.51)测量,治疗组患者与对照组患者相比未显示出更好的结局。本研究结果表明,接受VRT的患者并未比处于等待名单中的患者取得更好的结局。