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肝脏中球瘤的罕见位置:一例报告及文献综述

Unusual location of the glomus tumour in the liver: A case report and literature review.

作者信息

Li Liang, Xu Qing-Xia, Zhang Xiang-Yu, Han Cui-Hong

机构信息

Department of Pathology, The No 1 People's Hospital of Jining City, Jining City, Shandong, People's Republic of China.

出版信息

Medicine (Baltimore). 2018 Jun;97(26):e11294. doi: 10.1097/MD.0000000000011294.

Abstract

RATIONALE

Liver glomus tumor is very rare, and only 6 cases have been reported. Herein, we report another case of liver glomus tumor and the clinicopathological features are summarized.

PATIENT CONCERNS

An 18-year-old male patient was admitted due to hypertension and arrhythmia for 4 days.

DIAGNOSES

Abdominal enhanced CT revealed a 6.0-cm solid and cystic mass in the left liver lobe. The mass was collected by hepatic lobectomy. Microscopically, the tumor cells were round or oval, and had no malignant features and no evident atypia. Immumohistochemically, tumor cells were positive for positive for SMA and vimentin, but partially positive for syn, CD34 and desmin. He was pathologically diagnosed with liver glomus tumor.

INTERVENTIONS

The patient underwent a left hepatic lobectomy.

OUTCOMES

After surgery, this patient was followed up for 6 months, and metastasis/recurrence was not observed.

LESSONS

Primary liver glomus tumor has no specific clinical manifestations, and imaging examinations have limitations for its diagnosis. Immunostaining for SMA and vimentin is necessary to prove the diagnosis. Complete resection is strongly advised and it has a favorable prognosis.

摘要

理论依据

肝脏血管球瘤非常罕见,仅报道过6例。在此,我们报告另一例肝脏血管球瘤病例并总结其临床病理特征。

患者情况

一名18岁男性患者因高血压和心律失常4天入院。

诊断

腹部增强CT显示左肝叶有一个6.0厘米的实性和囊性肿块。通过肝叶切除术切除该肿块。显微镜下,肿瘤细胞呈圆形或椭圆形,无恶性特征且无明显异型性。免疫组化显示,肿瘤细胞平滑肌肌动蛋白(SMA)和波形蛋白呈阳性,但突触素、CD34和结蛋白部分呈阳性。他被病理诊断为肝脏血管球瘤。

干预措施

患者接受了左肝叶切除术。

结果

术后对该患者进行了6个月的随访,未观察到转移/复发。

经验教训

原发性肝脏血管球瘤无特异性临床表现,影像学检查对其诊断有局限性。SMA和波形蛋白免疫染色对确诊很有必要。强烈建议完整切除,其预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f629/6039582/2236f290a31e/medi-97-e11294-g001.jpg

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