浑浊生物介质中光传播与散射的数值模拟
Numerical Simulation of Light Propagation and Scattering in Turbid Biological Media.
作者信息
Lopatin V V, Priezzhev A V, Fedoseev V V
机构信息
General Physics and Wave Processes Department of the Physical Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia.
出版信息
Crit Rev Biomed Eng. 2017;45(1-6):99-118. doi: 10.1615/CritRevBiomedEng.v45.i1-6.50.
This article considers the processes of light propagation and scattering in biological tissues. The results obtained made it possible to estimate basic signal parameters and their dependence on various optical parameters with respect to the laser Doppler flowmeter and laser Doppler microscope. We also developed a new method to determine the indicatrix asymmetry of single and multiple light scattering by a suspension of oriented spheroidal particles that simulated erythrocytes in a shear flow. It was found that the angular dependence of the asymmetry index provides information on the shape and orientation of particles. In addition, we obtained single scattering indicatrices, which may improve the accuracy of computer simulation of light scattering by blood.
本文研究了光在生物组织中的传播和散射过程。所获得的结果使得能够针对激光多普勒血流仪和激光多普勒显微镜估计基本信号参数及其对各种光学参数的依赖性。我们还开发了一种新方法，用于确定在剪切流中模拟红细胞的取向球形颗粒悬浮液的单次和多次光散射的指示不对称性。发现不对称指数的角度依赖性提供了有关颗粒形状和取向的信息。此外，我们获得了单次散射指示，这可能会提高血液光散射计算机模拟的准确性。
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