Department of Clinical Medicine and Surgery, Oncology Unit, University of Naples Federico II, Naples, Italy.
The Institute of Cancer Research, 15 Cotswold Road, Sutton, London, UK.
Future Oncol. 2018 Jul;14(16):1591-1599. doi: 10.2217/fon-2017-0670. Epub 2018 Jun 29.
Testicular germ cell tumors (TGCTs) are the most prevalent malignancies in young Caucasian men. Clinical stage I (CSI) TGCTs present the highest cure rate and treatment options after orchiectomy depend on histology and risk factors. Nevertheless, the management of CSI TGCTs is controversial due to the availability of multiple treatments and the lack of randomized trials. An integrated multidisciplinary approach that includes clinicians (surgeons, radiotherapists and oncologists) and psychologists is crucial to maximize the patients' compliance and must be acknowledged with appropriate tools. The aim of our work is to review the oncological and psychological aspects of the decision-making process, discussing the fundamental role of the patient involvement in the personalized management of CSI TGCTs.
睾丸生殖细胞肿瘤（TGCTs）是年轻白种男性中最常见的恶性肿瘤。临床 I 期（CSI）TGCTs 的治愈率最高，睾丸切除术的治疗选择取决于组织学和危险因素。然而，由于存在多种治疗方法和缺乏随机试验，CSI TGCTs 的治疗存在争议。包括临床医生（外科医生、放疗师和肿瘤学家）和心理学家在内的综合多学科方法对于最大限度地提高患者的依从性至关重要，并且必须通过适当的工具来承认这一点。我们的工作旨在回顾决策过程中的肿瘤学和心理学方面，讨论患者参与 CSI TGCTs 个性化管理的基本作用。
