Weiss B, Cox C, Young M, Margen S, Williams J H
Department of Radiation Biology and Biophysics, University of Rochester School of Medicine and Dentistry, NY 14642.
Neurobehav Toxicol. 1979;1 Suppl 1:149-55.
Behavioral toxicology in the natural environment can be considered a special branch of epidemiology. Behavioral epidemiology, because it typically relies on complex functional criteria, faces all of the problems of behavior measurement posed by uncontrollable variation, and amplified even further by chemical exposure. Many such issues arose in a study of behavioral responses to artificial food colors in children. Difficulties in employing Applied Behavioral Analysis in such a context run the gamut from selection of retrospective criteria to appropriate statistical models.
自然环境中的行为毒理学可被视为流行病学的一个特殊分支。行为流行病学由于通常依赖复杂的功能标准,面临着由不可控变异带来的行为测量的所有问题,而化学暴露会进一步放大这些问题。在一项关于儿童对人工食用色素的行为反应的研究中就出现了许多此类问题。在这种情况下应用行为分析的困难涵盖了从回顾性标准的选择到适当的统计模型等一系列问题。