Nguyen Linda Trang, Yang David, Vien Lee
Veterans Affairs Palo Alto Health Care System, Palo Alto, California *
Optom Vis Sci. 2018 Jul;95(7):616-620. doi: 10.1097/OPX.0000000000001245.
Transitory corneal epithelial macrocysts associated with scleral contact lens wear post-penetrating keratoplasty are observed in areas of corneal edema. The macrocysts do not appear to result in complications that would prevent successful wear of scleral contact lenses.
The purpose of this study is to report three cases of transitory corneal epithelial macrocysts associated with scleral lenses in post-penetrating keratoplasty corneas.
Three cases including anterior segment photographs and anterior segment optical coherence tomography highlight the clinical presentation of transient corneal epithelial macrocysts.
Corneal edema and anatomical alterations after penetrating keratoplasty along with the negative pressure underneath a scleral contact lens are hypothesized to have caused the transient epithelial macrocysts observed in these cases. Because of the transitory nature of these cysts without evidence of consequent corneal damage or cyst rupture over years of observance, we believe that it is safe for these patients to continue wearing scleral contact lenses with routine follow-up.
穿透性角膜移植术后佩戴巩膜接触镜时，在角膜水肿区域可观察到与巩膜接触镜相关的暂时性角膜上皮大囊肿。这些大囊肿似乎不会导致妨碍巩膜接触镜成功佩戴的并发症。
本研究旨在报告3例穿透性角膜移植术后角膜出现与巩膜镜相关的暂时性角膜上皮大囊肿的病例。
3例病例包括眼前节照片和眼前节光学相干断层扫描，突出了暂时性角膜上皮大囊肿的临床表现。
据推测，穿透性角膜移植术后的角膜水肿和解剖结构改变，以及巩膜接触镜下方的负压，导致了这些病例中观察到的暂时性上皮大囊肿。由于这些囊肿具有暂时性，且在多年观察中没有角膜损伤或囊肿破裂的证据，我们认为这些患者在常规随访的情况下继续佩戴巩膜接触镜是安全的。
