USC Roski Eye Institute, University of Southern California, 1450 San Pablo Street, 4th Floor, Los Angeles, CA 90033, USA.
Cont Lens Anterior Eye. 2018 Oct;41(5):463-468. doi: 10.1016/j.clae.2018.05.002. Epub 2018 May 26.
With the increased fitting of scleral lenses by eye care practitioners, complications with lens wear need to be considered. Several prior studies have addressed complications specific to scleral lens wear and the incidence of hypoxia with extended wear, but few report the presence of epithelial bullae. This case series investigates three patients with differing ocular surface diseases, yet all developed transient epithelial bullae with concurrent large diameter scleral lens wear. These bullae appear to form due to weakened connections in the corneal epithelium at the level of basement membrane and Bowman's layer and flatten within minutes of lens removal. These bullae need to be further studied, as they can increase the patient's risk of epithelial defects, infections, and other complications in already compromised corneas.
随着眼科医生对巩膜镜片适配的增加，需要考虑镜片佩戴的并发症。有几项先前的研究针对巩膜镜片佩戴的具体并发症和长时间佩戴导致的缺氧发生率进行了探讨，但很少有报告提到上皮水疱的存在。本病例系列研究了三例患有不同眼部疾病的患者，但所有患者均在同时佩戴大直径巩膜镜片时出现短暂性上皮水疱。这些水疱似乎是由于角膜上皮在基底膜和鲍曼层水平的连接减弱而形成的，并在镜片取出后几分钟内变平。这些水疱需要进一步研究，因为它们会增加已经受损角膜发生上皮缺损、感染和其他并发症的风险。
