• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

肾细胞癌的放射治疗。

Radiation therapy in renal cell carcinoma.

机构信息

Department of Radiotherapy, Policlinico Umberto I "Sapienza" University of Rome, Viale Regina Elena 326, 00161, Rome, Italy.

Department of Radiotherapy, Policlinico Umberto I "Sapienza" University of Rome, Viale Regina Elena 326, 00161, Rome, Italy.

出版信息

Crit Rev Oncol Hematol. 2018 Aug;128:82-87. doi: 10.1016/j.critrevonc.2018.06.002. Epub 2018 Jun 12.

DOI:10.1016/j.critrevonc.2018.06.002
PMID:29958634
Abstract

Renal cell carcinoma (RCC) is classically regarded as extremely resistant to classical fractionated radiation therapy (RT). Nowadays, there is convincing data supporting RCC radiosensitivity to high fraction doses, which may represent an ideal issue for new treatment strategies in primary and oligometastatic RCC disease. This review discusses the role of RT in RCC and its potential therapeutic scenario focusing on the most interesting clinical trials.

摘要

肾细胞癌 (RCC) 通常被认为对经典的分割放疗 (RT) 具有极强的抵抗力。如今，有令人信服的数据支持 RCC 对高分割剂量的辐射敏感性，这可能是原发性和寡转移 RCC 疾病新治疗策略的理想问题。本综述讨论了 RT 在 RCC 中的作用及其潜在的治疗方案，重点介绍了最有趣的临床试验。

相似文献

1
Radiation therapy in renal cell carcinoma.肾细胞癌的放射治疗。
Crit Rev Oncol Hematol. 2018 Aug;128:82-87. doi: 10.1016/j.critrevonc.2018.06.002. Epub 2018 Jun 12.
2
Current Role of Radiotherapy for Renal-Cell Carcinoma: Review.放射治疗在肾细胞癌中的当前作用：综述
Clin Genitourin Cancer. 2017 Apr;15(2):183-187. doi: 10.1016/j.clgc.2016.09.004. Epub 2016 Sep 19.
3
Radiotherapy for renal-cell carcinoma.肾细胞癌的放射治疗。
Lancet Oncol. 2014 Apr;15(4):e170-7. doi: 10.1016/S1470-2045(13)70569-2.
4
Radiotherapy and Renal Cell Carcinoma: A Continuing Saga.放疗与肾细胞癌：一个持续的故事。
In Vivo. 2021 May-Jun;35(3):1365-1377. doi: 10.21873/invivo.12389. Epub 2021 Apr 28.
5
Radiotherapy for renal cell carcinoma: renaissance of an overlooked approach.肾癌的放射治疗：被忽视方法的复兴。
Nat Rev Urol. 2017 Sep;14(9):549-563. doi: 10.1038/nrurol.2017.87. Epub 2017 Jun 20.
6
Stereotactic Body Radiotherapy for Kidney Cancer: Ready for Prime Time?立体定向体部放疗治疗肾癌：是否已准备好应用于临床？
Clin Oncol (R Coll Radiol). 2023 Mar;35(3):163-176. doi: 10.1016/j.clon.2022.11.008. Epub 2022 Nov 25.
7
Role of Radiation in Treatment of Renal Cell Carcinoma.放射治疗在肾细胞癌治疗中的作用
Hematol Oncol Clin North Am. 2023 Oct;37(5):921-924. doi: 10.1016/j.hoc.2023.04.015. Epub 2023 May 26.
8
Incorporating Stereotactic Ablative Radiotherapy into the Multidisciplinary Management of Renal Cell Carcinoma.将立体定向消融放疗纳入肾细胞癌的多学科综合管理。
Curr Oncol. 2023 Dec 1;30(12):10283-10298. doi: 10.3390/curroncol30120749.
9
Hypofractionated postoperative irradiation in localized renal cell cancer: A case report and pertinent literature review.局限性肾细胞癌术后大分割放疗：1例报告及相关文献综述
J Cancer Res Ther. 2018;14(Supplement):S260-S262. doi: 10.4103/0973-1482.172711.
10
Radiation Therapy for Patients with Advanced Renal Cell Carcinoma.晚期肾细胞癌患者的放射治疗。
Urol Clin North Am. 2020 Aug;47(3):399-411. doi: 10.1016/j.ucl.2020.04.011. Epub 2020 Jun 8.

引用本文的文献

1
Stereotactic Body Radiation Therapy (SBRT) for Renal Cell Carcinoma with Inferior Vena Cava Tumor Thrombus.立体定向体部放射治疗（SBRT）用于治疗伴有下腔静脉肿瘤血栓的肾细胞癌。
Cancers (Basel). 2025 Feb 19;17(4):710. doi: 10.3390/cancers17040710.
2
Clinically Silent, Metastatic Renal Cell Carcinoma Detected on Routine Screening Mammogram: A Report of a Rare Case and Review of Literature.常规筛查乳房X光检查发现的临床隐匿性转移性肾细胞癌：1例罕见病例报告及文献复习
Cureus. 2023 Nov 6;15(11):e48352. doi: 10.7759/cureus.48352. eCollection 2023 Nov.
3
Cryoablation for the Treatment of Kidney Cancer: Comparison With Other Treatment Modalities and Review of Current Treatment.
冷冻消融治疗肾癌：与其他治疗方式的比较及当前治疗综述
Cureus. 2022 Nov 7;14(11):e31195. doi: 10.7759/cureus.31195. eCollection 2022 Nov.
4
Black Phosphorus Quantum Dots Enhance the Radiosensitivity of Human Renal Cell Carcinoma Cells through Inhibition of DNA-PKcs Kinase.黑磷量子点通过抑制 DNA-PKcs 激酶增强人肾细胞癌细胞的放射敏感性。
Cells. 2022 May 16;11(10):1651. doi: 10.3390/cells11101651.
5
Sohlh2 Inhibits the Malignant Progression of Renal Cell Carcinoma by Upregulating Klotho DNMT3a.Sohlh2通过上调Klotho和DNMT3a抑制肾细胞癌的恶性进展。
Front Oncol. 2022 Jan 19;11:769493. doi: 10.3389/fonc.2021.769493. eCollection 2021.
6
LINC02532 Contributes to Radiosensitivity in Clear Cell Renal Cell Carcinoma through the miR-654-5p/YY1 Axis.LINC02532 通过 miR-654-5p/YY1 轴促进肾透明细胞癌的放射敏感性。
Molecules. 2021 Nov 22;26(22):7040. doi: 10.3390/molecules26227040.
7
CircESRP1 inhibits clear cell renal cell carcinoma progression through the CTCF-mediated positive feedback loop.环状 RNA ESRP1 通过 CTCF 介导的正反馈回路抑制肾透明细胞癌的进展。
Cell Death Dis. 2021 Nov 13;12(11):1081. doi: 10.1038/s41419-021-04366-4.
8
ANGPTL3 Overexpression Suppresses the Development of Oncogenic Properties in Renal Cell Carcinoma via the Wnt/-Catenin Signaling Pathway and Predicts Good Prognosis.ANGPTL3 过表达通过 Wnt/-Catenin 信号通路抑制肾细胞癌的致癌特性发展，并预测良好的预后。
Dis Markers. 2021 Aug 24;2021:2863856. doi: 10.1155/2021/2863856. eCollection 2021.
9
Identification of RNA Transcript Makers Associated With Prognosis of Kidney Renal Clear Cell Carcinoma by a Competing Endogenous RNA Network Analysis.通过竞争性内源性RNA网络分析鉴定与肾透明细胞癌预后相关的RNA转录本标志物
Front Genet. 2020 Oct 15;11:540094. doi: 10.3389/fgene.2020.540094. eCollection 2020.
10
Radiation and Checkpoint Inhibitor Immunotherapy Lead to Long Term Disease Control in a Metastatic RCC patient With Brain Metastases.放射治疗和检查点抑制剂免疫疗法使一名患有脑转移的转移性肾细胞癌患者实现长期疾病控制。
Front Oncol. 2020 Sep 23;10:566070. doi: 10.3389/fonc.2020.566070. eCollection 2020.