Reconstructive Surgery & Regenerative Medicine Research Group, Institute of Life Science 2, Swansea University Medical School, Swansea, UK, SA2 8PP; The Welsh Centre for Burns and Plastic Surgery, Morriston Hospital, Swansea, UK, SA6 6NL.
School of Medicine, Cardiff University, Cardiff, UK, CF14 4XN.
J Affect Disord. 2018 Oct 15;239:1-10. doi: 10.1016/j.jad.2018.06.013. Epub 2018 Jun 20.
Facial scarring can have a dramatic effect on a patient's psychological health and wellbeing and present unique management challenges. This patient population remains poorly characterised in the contemporary literature.
To evaluate the prevalence of, and risk factors associated with affective disorders in adult patients with facial scars.
A systematic review was conducted using a protocol registered with PROSPERO and in line with the PRISMA statement. A comprehensive search of the literature was conducted using PubMed, MEDLINE, EMBASE, PSYCHInfo and The Cochrane Library.
Twenty one studies were included, with a total of 2,394 participants. Using a random effects model, the weighted pooled prevalence of anxiety was 26.1% (95% CI 17.9%-36.3%) and the weighted pooled prevalence of depression was 21.4% (95% CI 15.4%-29.0%). Studies identified female gender, past psychiatric history and violent causation as factors associated with anxiety and depression.
Included studies were limited to those published in peer reviewed journals. Longitudinal trends in both anxiety and depression were limited by a short duration of follow up.
There is a high and persistent burden of affective disorders in patients with facial scars. Additional research is required to further characterise this population and develop effective management strategies.
面部疤痕会对患者的心理健康和幸福感产生巨大影响，并带来独特的管理挑战。这一患者群体在当代文献中描述不足。
评估成年面部疤痕患者中情感障碍的患病率和相关风险因素。
使用 PROSPERO 注册的方案和 PRISMA 声明进行系统评价。使用 PubMed、MEDLINE、EMBASE、PSYCHInfo 和 The Cochrane Library 对文献进行全面检索。
共纳入 21 项研究，共计 2394 名参与者。使用随机效应模型，焦虑的加权汇总患病率为 26.1%（95%CI 17.9%-36.3%），抑郁的加权汇总患病率为 21.4%（95%CI 15.4%-29.0%）。研究确定女性性别、既往精神病史和暴力致伤是与焦虑和抑郁相关的因素。
纳入的研究仅限于发表在同行评审期刊上的研究。由于随访时间短，焦虑和抑郁的纵向趋势受到限制。
面部疤痕患者中存在高且持续的情感障碍负担。需要进一步研究以更好地描述这一人群并制定有效的管理策略。
