Vehling Sigrun, Koch Uwe, Ladehoff Natalie, Schön Gerhard, Wegscheider Karl, Heckl Ulrike, Weis Joachim, Mehnert Anja
Institut und Poliklinik für Medizinische Psychologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg.
Psychother Psychosom Med Psychol. 2012 Jul;62(7):249-58. doi: 10.1055/s-0032-1309032. Epub 2012 May 14.
We aimed to systematically summarize the empirical evidence on the 4-week-, 12-month-, and lifetime prevalence of affective and anxiety disorders in cancer patients. We evaluated 89 English or German language original papers and systematic reviews that assessed the prevalence of affective and anxiety disorders using structured clinical interviews published between 1995 and 2010. Adjusted prevalence rates were calculated using a random-intercept model. The pooled adjusted 4-week prevalence of affective disorders was 11.1% (95% CI 8.1-15.1), and 10.8% (95% CI 6.8-16.7) based on German studies. The pooled adjusted 4-week prevalence of anxiety disorders was 10.2% (95% CI 6.9-14.8), and 13.5% (95% CI 7.1-24.3) based on German studies. The findings show the need for further research on representative studies that take into account the range of psychosocial stressors and supportive care needs in addition to the prevalence of mental disorders.
我们旨在系统总结癌症患者情感障碍和焦虑症4周、12个月及终生患病率的实证证据。我们评估了89篇英文或德文原创论文及系统评价,这些研究使用1995年至2010年间发表的结构化临床访谈评估情感障碍和焦虑症的患病率。采用随机截距模型计算调整后的患病率。情感障碍的合并调整后4周患病率为11.1%(95%CI 8.1 - 15.1),基于德国研究的结果为10.8%(95%CI 6.8 - 16.7)。焦虑症的合并调整后4周患病率为10.2%(95%CI 6.9 - 14.8),基于德国研究的结果为13.5%(95%CI 7.1 - 24.3)。研究结果表明,除了精神障碍患病率外,还需要针对考虑到一系列心理社会压力源和支持性护理需求的代表性研究开展进一步研究。