气体扩散对冲击波散射空化术中气泡持续时间的影响。
The influence of gas diffusion on bubble persistence in shock-scattering histotripsy.
机构信息
Department of Radiology and the Committee on Medical Physics, University of Chicago, Chicago, Illinois 60637, USA
Department of Radiology, University of Chicago, Chicago, Illinois 60637, USA
出版信息
J Acoust Soc Am. 2018 Jun;143(6):EL481. doi: 10.1121/1.5043081.
Abstract
Bubble cloud persistence reduces the efficacy of mechanical liquefaction with shock-scattering histotripsy. In this study, the contribution of gas transfer to bubble longevity was investigated in silico by solving the equations for bubble oscillations and diffusion in parallel. The bubble gas content increased more than 5 orders of magnitude during the expansion phase, arresting the inertial collapse. The residual gas bubble required more than 15 ms for passive dissolution post excitation, consistent with experimental observation. These results demonstrate gas diffusion is an important factor in the persistence of histotripsy-induced cavitation.
摘要
气泡云的持续存在降低了机械液化与冲击波碎石联合应用的效果。在这项研究中，通过同时求解气泡振荡和扩散方程，对气体转移对气泡寿命的贡献进行了计算机模拟研究。在膨胀阶段，气泡中的气体含量增加了超过 5 个数量级，从而阻止了惯性坍塌。在激发后，残余气泡需要超过 15 毫秒才能进行被动溶解，这与实验观察结果一致。这些结果表明，气体扩散是冲击波碎石诱导空化持续存在的一个重要因素。
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2
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Phys Med Biol. 2018 Jan 9;63(2):025011. doi: 10.1088/1361-6560/aa9a2f.
3
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IEEE Trans Med Imaging. 2018 Jan;37(1):106-115. doi: 10.1109/TMI.2017.2735238. Epub 2017 Aug 2.
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5
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6
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7
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