NHS National Services Scotland, Edinburgh, UK.
Department of Medicine, Dumfries and Galloway Royal Infirmary, Dumfries, UK.
BMJ Open. 2018 Jun 30;8(6):e021432. doi: 10.1136/bmjopen-2017-021432.
It is increasingly recognised that large numbers of hospital inpatients have entered the last year of their lives.
To establish the likelihood of death within 12 months of admission to hospital; to examine the influence on survival of a cancer diagnosis made within the previous 5 years; to assess whether previous emergency admissions influenced mortality; and to compare mortality with that of the wider Scottish population.
Incident cohort study.
22 hospitals in Scotland.
This study used routinely collected data from 10 477 inpatients admitted as an emergency to medicine in 22 Scottish hospitals between 18 and 31 March 2015. These data were linked to national death records and the Scottish Cancer Registry.
1 year cohort mortality compared with that of the general Scottish population. Patient factors correlating with higher risk of mortality were identified using Cox regression.
There were 2346 (22.4%) deaths in the year following the census admission. Six hundred and ten patients died during that admission (5.8% of all admissions and 26% of all deaths) while 1736 died after the census admission (74% of all deaths). Malignant neoplasms (33.8%), circulatory diseases (22.5%) and respiratory disease (17.9%) accounted for almost three-quarters of all deaths. Mortality rose steeply with age and was five times higher at 1 year for patients aged 85 years and over compared with those who were under 60 years of age (41.9%vs7.9%) (p<0.001). Patients with cancer had a higher mortality rate than patients without a cancer diagnosis (55.6%vs16.6%) (p<0.001). Mortality was higher among patients with one or more emergency medical admissions in the previous year (30.1% v 15.1%) (p<0.001). Age/sex-standardised mortality was 110.4 (95% CI 104.4 to 116.5) for the cohort and 11.7 (95% CI 11.6 to 11.8) for the Scottish population, a 9.4-fold increase in risk.
These data may help identify groups of patients admitted to hospital as medical emergencies who are at greatest risk of dying not only during admission but also in the following 12 months.
越来越多的人认识到,大量住院患者已经进入生命的最后一年。
确定入院后 12 个月内死亡的可能性;检查过去 5 年内诊断出的癌症对生存的影响;评估以前的急诊入院是否影响死亡率;并将死亡率与更广泛的苏格兰人群进行比较。
前瞻性队列研究。
苏格兰 22 家医院。
本研究使用了 2015 年 3 月 18 日至 31 日期间苏格兰 22 家医院急诊收治的 10477 名内科住院患者的常规收集数据。这些数据与国家死亡记录和苏格兰癌症登记处进行了链接。
与苏格兰一般人群相比,1 年队列死亡率。使用 Cox 回归确定与更高死亡率相关的患者因素。
在普查入院后的一年中有 2346 人(22.4%)死亡。610 人在该入院期间死亡(所有入院人数的 5.8%,所有死亡人数的 26%),1736 人在普查入院后死亡(所有死亡人数的 74%)。恶性肿瘤(33.8%)、循环系统疾病(22.5%)和呼吸系统疾病(17.9%)占所有死亡人数的近四分之三。死亡率随年龄急剧上升,85 岁及以上患者的 1 年死亡率是 60 岁以下患者的五倍(41.9%对 7.9%)(p<0.001)。有癌症的患者死亡率高于无癌症诊断的患者(55.6%对 16.6%)(p<0.001)。在过去一年中有一次或多次急诊医疗入院的患者死亡率更高(30.1%对 15.1%)(p<0.001)。年龄/性别标准化死亡率为队列的 110.4(95%CI 104.4 至 116.5)和苏格兰人口的 11.7(95%CI 11.6 至 11.8),风险增加了 9.4 倍。
这些数据可能有助于确定作为急诊入院的内科患者群体,这些患者不仅在入院期间而且在接下来的 12 个月内死亡的风险最高。