Division of General Internal Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Cancer. 2010 Feb 15;116(4):998-1006. doi: 10.1002/cncr.24761.
Guidelines recommend advanced care planning for terminally ill patients with <1 year to live. Few data are available regarding when physicians and their terminally ill patients typically discuss end-of-life issues.
A national survey was conducted of physicians caring for cancer patients about timing of discussions regarding prognosis, do not resuscitate (DNR) status, hospice, and preferred site of death with their terminally ill patients. Logistic regression was used to identify physician and practice characteristics associated with earlier discussions.
Among 4074 respondents, 65% would discuss prognosis "now" (defined as patient has 4 months to 6 months to live, asymptomatic). Fewer would discuss DNR status (44%), hospice (26%), or preferred site of death (21%) immediately, with most physicians waiting for patient symptoms or until there are no more treatments to offer. In multivariate analyses, younger physicians more often discussed prognosis, DNR status, hospice, and site of death "now" (all P < .05). Surgeons and oncologists were more likely than noncancer specialists to discuss prognosis "now" (P = .008), but noncancer specialists were more likely than cancer specialists to discuss DNR status, hospice, and preferred site of death "now" (all P < .001).
Most physicians report they would not discuss end-of-life options with terminally ill patients who are feeling well, instead waiting for symptoms or until there are no more treatments to offer. More research is needed to understand physicians' reasons for timing of discussions and how their propensity to aggressively treat metastatic disease influences timing, as well as how the timing of discussions influences patient and family experiences at the end of life.
指南建议对预计生存时间不足 1 年的终末期患者进行高级医疗照护计划。关于医生及其终末期患者通常何时讨论临终问题,仅有少量数据。
对治疗癌症患者的医生进行了一项全国性调查,了解他们与终末期患者讨论预后、不复苏(DNR)状态、临终关怀和首选死亡地点的时间。使用逻辑回归来确定与更早讨论相关的医生和实践特征。
在 4074 名受访者中,65%的人会“现在”(定义为患者有 4 至 6 个月的生存时间,无症状)讨论预后。讨论 DNR 状态(44%)、临终关怀(26%)或首选死亡地点(21%)的人较少,大多数医生会等待患者出现症状,或直到没有更多的治疗方法可用。在多变量分析中,年轻医生更常“现在”讨论预后、DNR 状态、临终关怀和死亡地点(均 P <.05)。外科医生和肿瘤学家比非癌症专家更有可能“现在”讨论预后(P =.008),但非癌症专家比癌症专家更有可能“现在”讨论 DNR 状态、临终关怀和首选死亡地点(均 P <.001)。
大多数医生表示,他们不会与感觉良好的终末期患者讨论临终选择,而是等待出现症状,或直到没有更多的治疗方法可用。需要进一步研究以了解医生讨论时间的原因以及他们积极治疗转移性疾病的倾向如何影响时间安排,以及讨论时间如何影响患者和家属在生命末期的体验。