Crouch Simone H, Ware Lisa J, Gafane-Matemane Lebo F, Kruger Herculina S, Van Zyl Tertia, Van der Westhuizen Bianca, Schutte Aletta E
Hypertension in Africa Research Team (HART), North-West University, Potchefstroom, South Africa.
MRC Research Unit: Hypertension and Cardiovascular Disease, North-West University, Potchefstroom, South Africa.
J Clin Hypertens (Greenwich). 2018 Jul 1;20(8):1193-202. doi: 10.1111/jch.13329.
Obesity and salt intake are both established factors contributing to cardiovascular disease development. Recently, studies found a controversial positive relationship between dietary salt and obesity. Therefore, the authors investigated whether obesity-related measures are associated with 24-hour urinary sodium in a healthy biethnic population. The study included 761 adults (20-30 years) with complete 24-hour urinary sodium, anthropometry, and bioelectrical impedance measurements. In single regression analyses all obesity-related measures related positively with 24-hour urinary sodium (P ≤ .008). However, with multivariate adjustments for energy intake, accelerometery, age, sex, black and white ethnicity, and other covariates, only body surface area (BSA) remained independently associated with 24-hour urinary sodium (R = 0.72, β = .05, P = .039). To conclude, we found a consistent and robust positive relationship between BSA and estimated salt intake - but not with traditional obesity measures such as body mass index (BMI). Further studies are needed to investigate body surface area and potentially, skin area, in salt handling.
肥胖和盐摄入都是导致心血管疾病发生的既定因素。最近,研究发现饮食中的盐与肥胖之间存在有争议的正相关关系。因此,作者调查了在一个健康的双种族人群中,与肥胖相关的指标是否与24小时尿钠有关。该研究纳入了761名成年人(20至30岁),他们均有完整的24小时尿钠、人体测量学和生物电阻抗测量数据。在单因素回归分析中,所有与肥胖相关的指标均与24小时尿钠呈正相关(P≤0.008)。然而,在对能量摄入、加速度计测量值、年龄、性别、黑人和白人种族以及其他协变量进行多因素调整后,只有体表面积(BSA)仍与24小时尿钠独立相关(R = 0.72,β = 0.05,P = 0.039)。总之,我们发现体表面积与估计的盐摄入量之间存在一致且显著的正相关关系——但与体重指数(BMI)等传统肥胖指标无关。需要进一步研究来调查体表面积以及可能的皮肤面积在盐代谢中的作用。