Igenomix, Marostica, Vicenza, Italy.
Reproomics, Amsterdam, The Netherlands.
Panminerva Med. 2019 Mar;61(1):30-41. doi: 10.23736/S0031-0808.18.03506-1. Epub 2018 Jun 28.
Preimplantation genetic testing is a methodology aimed at the assessment of the genetic composition of an embryo. This diagnostic approach has been used in assisted reproduction for almost thirty years. During these years, the technologies used for embryo's genetic analysis have been continuously improved allowing the development of more precise, comprehensive and robust strategies that are clinically employed nowadays. In this review, the main diagnostic approaches used for embryo genetic and chromosomal assessment are described and discussed both from an embryological and genetic standpoint.
胚胎植入前遗传学检测是一种旨在评估胚胎遗传组成的方法。这种诊断方法在辅助生殖中已经使用了近三十年。在这几年中，用于胚胎遗传分析的技术不断得到改进，从而开发出更精确、全面和强大的策略，这些策略目前在临床上得到应用。在这篇综述中，从胚胎学和遗传学的角度描述和讨论了胚胎遗传和染色体评估中使用的主要诊断方法。
