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全膝关节置换术中近端与远端收肌管阻滞在疼痛控制和功能活动度方面的随机对照比较

A Randomized Comparison of Pain Control and Functional Mobility between Proximal and Distal Adductor Canal Blocks for Total Knee Replacement.

作者信息

Romano Christopher, Lloyd Andrew, Nair Singh, Wang Jenny Y, Viswanathan Shankar, Vydyanathan Amaresh, Gritsenko Karina, Shaparin Naum, Kosharskyy Boleslav

机构信息

Department of Anesthesiology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA.

Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.

出版信息

Anesth Essays Res. 2018 Apr-Jun;12(2):452-458. doi: 10.4103/aer.AER_17_18.

Abstract

BACKGROUND

Adductor canal blocks (ACBs) have become a popular technique for postoperative pain control in total knee arthroplasty patients. Proximal and distal ACB have been compared previously, but important postoperative outcomes have yet to be assessed.

AIMS

The primary objective of this study is to compare postoperative analgesia between proximal and distal ACB. Secondary outcomes include functional mobility, length of stay (LOS), and adverse events.

SETTINGS AND DESIGN

This study was a single-center, assessor-blinded, randomized trial.

SUBJECTS AND METHODS

Fifty-seven patients were randomly assigned to receive a proximal ( = 28) or distal ( = 29) ACB. A 20 mL bolus of 5 mg/mL ropivacaine was injected at the respective location followed by 2.0 mg/mL ropivacaine infusion for 24 h.

STATISTICAL ANALYSIS

The primary outcome was intra- and postoperative 24-h opioid consumption in intravenous (IV) morphine equivalents. Secondary outcomes include percentage change in timed "Up and Go" (TUG) times, LOS, and average postoperative pain scores. Continuous variables were compared using Student's -test.

RESULTS

The mean (±standard deviation) 24-h intra-and postoperative opioid consumption showed no difference between the proximal and distal groups (39.72 ± 23.6 and 41.28 ± 19.6 mg IV morphine equivalents, respectively, = 0.793). There was also no significant difference in the median [minimum, maximum] percentage change in TUG times relative to preoperative performance comparing proximal and distal ACB (334.0 [131, 1084] %-change and 458.5 [169, 1696] %-change, respectively, = 0.130). In addition, there were no differences in postoperative pain scores or LOS.

CONCLUSIONS

ACB performed at either proximal or distal locations shows no difference in postoperative pain measured by opioid consumption or pain scores. Better TUG performance seen in the proximal group was not statistically significant but might represent a clinically important difference in functional mobility.

摘要

背景

内收肌管阻滞(ACB)已成为全膝关节置换术患者术后疼痛控制的常用技术。先前已对近端和远端ACB进行了比较,但重要的术后结果尚未得到评估。

目的

本研究的主要目的是比较近端和远端ACB术后的镇痛效果。次要结果包括功能活动能力、住院时间(LOS)和不良事件。

设置与设计

本研究是一项单中心、评估者盲法的随机试验。

研究对象与方法

57例患者被随机分配接受近端(n = 28)或远端(n = 29)ACB。在相应位置注射20 mL 5 mg/mL的罗哌卡因推注,随后以2.0 mg/mL的罗哌卡因输注24小时。

统计分析

主要结果是术后24小时内静脉注射(IV)吗啡当量的阿片类药物消耗量。次要结果包括定时“起身走”(TUG)时间的百分比变化、LOS和术后平均疼痛评分。连续变量采用Student's t检验进行比较。

结果

近端和远端组术后24小时内平均(±标准差)阿片类药物消耗量无差异(分别为39.72±23.6和41.28±19.6 mg IV吗啡当量,P = 0.793)。比较近端和远端ACB,TUG时间相对于术前表现的中位数[最小值,最大值]百分比变化也无显著差异(分别为334.0 [131, 1084] %变化和458.5 [169, 1696] %变化,P = 0.130)。此外,术后疼痛评分或LOS也无差异。

结论

在近端或远端进行的ACB在通过阿片类药物消耗量或疼痛评分衡量的术后疼痛方面无差异。近端组更好的TUG表现虽无统计学意义,但可能代表功能活动能力方面的临床重要差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/647c/6020584/4584ba52b8cd/AER-12-452-g001.jpg

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