Martell K, Fairchild A, LeGerrier B, Sinha R, Baker S, Liu H, Ghose A, Olivotto I A, Kerba M
Department of Oncology, Tom Baker Cancer Centre, University of Calgary, Calgary.
Department of Oncology, Cross Cancer Institute, University of Alberta, Edmonton.
Curr Oncol. 2018 Jun;25(3):219-225. doi: 10.3747/co.25.3983. Epub 2018 Jun 28.
A comprehensive assessment of cannabis use by patients with cancer has not previously been reported. In this study, we aimed to characterize patient perspectives about cannabis and its use.
An anonymous survey about cannabis use was offered to patients 18 years of age and older attending 2 comprehensive and 2 community cancer centres, comprising an entire provincial health care jurisdiction in Canada (ethics id: hreba-17011).
Of 3138 surveys distributed, 2040 surveys were returned (65%), with 1987 being sufficiently complete for analysis (response rate: 63%). Of the respondents, 812 (41%) were less than 60 years of age; 45% identified as male, and 55% as female; and 44% had completed college or higher education.Of respondents overall, 43% reported any lifetime cannabis use. That finding was independent of age, sex, education level, and cancer histology. Cannabis was acquired through friends (80%), regulated medical dispensaries (10%), and other means (6%). Of patients with any use, 81% had used dried leaves.Of the 356 patients who reported cannabis use within the 6 months preceding the survey (18% of respondents with sufficiently complete surveys), 36% were new users. Their reasons for use included cancer-related pain (46%), nausea (34%), other cancer symptoms (31%), and non-cancer-related reasons (56%).
The survey demonstrated that prior cannabis use was widespread among patients with cancer (43%). One in eight respondents identified at least 1 cancer-related symptom for which they were using cannabis.
此前尚未有关于癌症患者大麻使用情况的综合评估报告。在本研究中，我们旨在描述患者对大麻及其使用的看法。
向年龄在18岁及以上、在2家综合癌症中心和2家社区癌症中心就诊的患者进行了一项关于大麻使用情况的匿名调查，这些中心覆盖了加拿大一个省级医疗保健辖区（伦理编号：hreba - 17011）。
在分发的3138份调查问卷中，回收了2040份（65%），其中1987份足够完整可用于分析（回复率：63%）。在受访者中，812人（41%）年龄小于60岁；45%为男性，55%为女性；44%完成了大学或更高层次的教育。在所有受访者中，43%报告曾在一生中使用过大麻。这一发现与年龄、性别、教育水平和癌症组织学无关。大麻通过朋友获取的占80%，通过合法的医疗药房获取的占10%，通过其他途径获取的占6%。在曾使用过大麻的患者中，81%使用过干叶。在调查前6个月内报告使用过大麻的356名患者（占回复足够完整的受访者的18%）中，36%是新使用者。他们使用大麻的原因包括与癌症相关的疼痛（46%）、恶心（34%）、其他癌症症状（31%）以及与癌症无关的原因（56%）。
该调查表明，癌症患者中此前使用过大麻的情况很普遍（43%）。八分之一的受访者指出至少有1种他们正在使用大麻缓解的与癌症相关的症状。
