Fraimovitch Margarita, Weinstein Julio
Meuhedet Health Fund.
Diabetes Unit, Wolfson Medical Center.
Harefuah. 2018 Jun;157(6):361-364.
There is a variety of native and foreign-born diabetes patients from all over the world in Israel. A combination of genetic and acquired factors leads to high-rate spreading of diabetes mellitus. Consequently, certain differences exist in a number of features of the disease typical for Israeli-born patients and for immigrants.
This retrospective research has been conducted within a population of diabetes patients aged over 40 years in a group of immigrant and a group of Israeli-born patients (119 immigrants and 65 Israeli-born patients). Parameters checked were: background diseases, family history, types of treatment, risk factors and complications.
In the group of immigrants, the percentage of male patients with negative family history was much higher than the percentage of male patients with positive family history of diabetes mellitus (16.8% vs. 6.5% respectively). Relating immigrants with positive family history, micro-vascular complications were 3 times more prevalent than macro-vascular complications (30.3% vs. 9.2% respectively). In the group of Israeli-born patients there was a significant difference in the level of micro- and macro-vascular complications among the patients with positive and negative family history (32% vs. 12.3% for macro-vascular and 27.7 vs. 10.8% for micro-vascular complications).
(1) The percentage of males suffering from diabetes mellitus with negative family history is much higher than that with positive family history (16.8% vs. 6.5%); (2) The level of micro-vascular complications among immigrants with positive family history is 3.3 times higher than the level of macro-vascular complications among immigrants with positive family history of diabetes mellitus (30.3% vs. 9.2%).
以色列有来自世界各地的各类本地和外国出生的糖尿病患者。遗传因素和后天因素共同作用导致糖尿病的高发病率。因此，以色列出生的患者和移民在该疾病的一些特征上存在某些差异。
这项回顾性研究在一组40岁以上的糖尿病患者中进行，分为移民组和以色列出生的患者组（119名移民和65名以色列出生的患者）。检查的参数包括：基础疾病、家族史、治疗类型、危险因素和并发症。
在移民组中，家族史阴性的男性患者比例远高于有糖尿病家族史阳性的男性患者比例（分别为16.8%和6.5%）。在家族史阳性的移民中，微血管并发症的发生率是大血管并发症的3倍（分别为30.3%和9.2%）。在以色列出生的患者组中，家族史阳性和阴性的患者在微血管和大血管并发症水平上存在显著差异（大血管并发症分别为32%和12.3%，微血管并发症分别为27.7%和10.8%）。
（1）家族史阴性的糖尿病男性患者比例远高于家族史阳性的患者（16.8%对6.5%）；（2）家族史阳性的移民中微血管并发症水平比家族史阳性的糖尿病移民中大血管并发症水平高3.3倍（30.3%对9.2%）。
