Wu Xu-Yue, Zou Hua, Zhu Rong, Wang Jing-Guo
School of Environment and Civil Engineering, Jiangnan University, Wuxi 214122, China.
Jiangsu Collaborative Innovation Center of Technology and Material of Water Treatment, Suzhou 215009, China.
Huan Jing Ke Xue. 2016 Dec 8;37(12):4596-4604. doi: 10.13227/j.hjkx.201603005.
In order to assess the contamination degree and ecological risk of antibiotics in Gonghu Bay, Taihu Lake, the contamination characteristics of four kinds of antibiotics (tetracycline, quinolones, sulfonamides and macrolides) in surface water of the Gonghu Bay were analyzed using high performance liquid chromatography and tandem mass spectrometry (HPLC-MS/MS). The results showed that 13 of the 16 target antibiotics were detected in the Gonghu Bay. The mass concentrations of the 13 antibiotics ranged 0.005-4.720 μg·L, and OTC was of the highest concentration. The detection level of antibiotics was also different between the northern and the southern parts of Gonghu Bay, and the mass concentration of tetracycline in the northern part was higher than that in the southern part. Moreover, the concentrations of quinolones and sulfonamides in the southern part were larger than those in the northern part. The potential ecological risks of the detected antibiotics were assessed via using the risk quotients (RQ) approach. The preliminary results showed that 5 kinds of antibiotics: OTC, NOR, OFL, CIP and ENR were at high risk, accounting for 38.5% and 4 kinds of antibiotics TC, CTC, ROX and SMX were at medium risk, accounting for 30.8% in the antibiotics detected in Gonghu Bay, while the others (SMR, SMP, SQX, TMP) were at low risk. Ecological risk assessment revealed that some risks were present in antibiotics in the Gonghu Bay. The tetracyclines and quinolones were particularly prominent, which should be drawn enough attention, and corresponding preventive measures should be taken as well.
为评估太湖贡湖湾抗生素的污染程度及生态风险，采用高效液相色谱 - 串联质谱法（HPLC - MS/MS）分析了贡湖湾地表水4种抗生素（四环素类、喹诺酮类、磺胺类和大环内酯类）的污染特征。结果表明，在贡湖湾检测出16种目标抗生素中的13种。这13种抗生素的质量浓度范围为0.005 - 4.720 μg·L，其中土霉素浓度最高。贡湖湾南北部抗生素的检出水平也存在差异，北部四环素的质量浓度高于南部。此外，南部喹诺酮类和磺胺类的浓度高于北部。采用风险商数（RQ）法对检测出的抗生素潜在生态风险进行评估。初步结果显示，土霉素、诺氟沙星、氧氟沙星、环丙沙星和恩诺沙星5种抗生素处于高风险，占贡湖湾检测出抗生素的38.5%；四环素、金霉素、罗红霉素和磺胺甲恶唑4种抗生素处于中风险，占30.8%；其他（磺胺间甲氧嘧啶、磺胺甲嘧啶、磺胺喹恶啉、甲氧苄啶）处于低风险。生态风险评估表明，贡湖湾抗生素存在一定风险。四环素类和喹诺酮类尤为突出，应予以足够重视，并采取相应预防措施。
