培养的3T3-L1脂肪细胞中甘油-3-磷酸脱氢酶mRNA含量：二丁酰环磷酸腺苷的调节作用
Glycerol-3-phosphate dehydrogenase mRNA content in cultured 3T3-L1 adipocytes: regulation by dibutyryl cyclic AMP.
作者信息
Bhandari B, Miller R E
出版信息
Biochem Biophys Res Commun. 1985 Sep 30;131(3):1193-7. doi: 10.1016/0006-291x(85)90217-7.
PMID:2996540
Abstract
Incubation of differentiated 3T3-L1 adipocytes with 0.5 mM dibutyryl cAMP plus 0.5 mM theophylline for 2 hours results in an 85% decrease in glycerol-3-phosphate dehydrogenase (G3PD) mRNA content. Incubation of the adipocytes with insulin (1 microgram/ml) up to 24 hrs yielded no significant change in the G3PD mRNA content compared with control.
摘要
将分化的3T3-L1脂肪细胞与0.5 mM二丁酰环磷腺苷（dibutyryl cAMP）加0.5 mM茶碱孵育2小时，导致甘油-3-磷酸脱氢酶（G3PD）mRNA含量降低85%。与对照组相比，将脂肪细胞与胰岛素（1微克/毫升）孵育长达24小时，G3PD mRNA含量没有显著变化。
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