[利用自旋捕获技术检测完整心脏线粒体中的超氧自由基]
[Detection of superoxide radicals in intact heart mitochondria by spin trapping].
作者信息
Ledenev A N, Popova E Iu, Ruuge E K
出版信息
Biofizika. 1985 Jul-Aug;30(4):708-9.
PMID:2996623
Abstract
Tiron (4,5-dihydroxybenzene-1,3-disulfonic acid, disodium salt) has been used as a spin trap to detect superoxide radicals produced by the rat heart mitochondria. In the presence of the oxidative phosphorylation uncoupler carbonyl cyanide (3-chlorophenyl)-hydrazone the superoxide production rate increases.
摘要
钛铁试剂（4,5-二羟基苯-1,3-二磺酸钠）已被用作自旋捕获剂，以检测大鼠心脏线粒体产生的超氧自由基。在氧化磷酸化解偶联剂羰基氰（3-氯苯基）腙存在的情况下，超氧产生速率会增加。
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