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结肠直肠手术后手术时间与不良事件之间的关系是什么?

What Is the Relationship between Operative Time and Adverse Events after Colon and Rectal Surgery?

作者信息

Poles Gabriela, Stafford Caitlin, Francone Todd, Roberts Patricia L, Ricciardi Rocco

机构信息

Department of Colorectal Surgery, Lahey Hospital & Medical Center, Burlington, Massachusetts, USA.

出版信息

Am Surg. 2018 May 1;84(5):712-716.

PMID:29966573
Abstract

We propose that prolonged colorectal surgery operative times are associated with increased 30-day adverse events. We identified a cohort from the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) from January 2005 through December 2012. Patients who underwent colectomy with primary anastomosis were selected using CPT codes. Operative time was categorized into short, average, and long based on mean operative times ±1 SD. NSQIP-approved multivariate models were used to identify associations between operative time and 30-day adverse events. A total of 113,615 patients underwent colorectal resection of which 46 per cent were laparoscopic and 12 per cent were identified as long operative times. Patients with long operative procedures had 34 per cent more superficial surgical site infections, 65 per cent more organ space infections, 69 per cent more abdominal dehiscences, 44 per cent more thrombotic complications, 45 per cent more urinary tract infections, 40 per cent more returns to the operating room, and 36 per cent more prolonged lengths of stay (P < 0.05 for all analyses). The multivariable analysis revealed an association between long operative times and increased adverse events despite adjustment for all NSQIP recommended covariates. Our results reveal increased 30-day adverse events with increased operative time. We propose that operative time may serve as a proxy for surgical complexity in colorectal surgery.

摘要

我们提出,结直肠手术时间延长与30天不良事件增加相关。我们从美国外科医师学会国家外科质量改进计划(NSQIP)中确定了一个队列,时间跨度为2005年1月至2012年12月。使用CPT编码选择接受一期吻合结肠切除术的患者。根据平均手术时间±1个标准差,将手术时间分为短、中、长三类。使用NSQIP批准的多变量模型来确定手术时间与30天不良事件之间的关联。共有113,615例患者接受了结直肠切除术,其中46%为腹腔镜手术,12%被确定为手术时间长。手术时间长的患者浅表手术部位感染多34%,器官间隙感染多65%,腹部切口裂开多69%,血栓形成并发症多44%,尿路感染多45%,返回手术室的次数多40%,住院时间延长多36%(所有分析P<0.05)。多变量分析显示,尽管对所有NSQIP推荐的协变量进行了调整,但手术时间长与不良事件增加之间仍存在关联。我们的结果显示,随着手术时间的增加,30天不良事件也会增加。我们提出,手术时间可作为结直肠手术中手术复杂性的一个替代指标。

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