Cojocari Nadejda, David Leonard
Department of General Surgery, Fundeni Clinical Institute, Bucharest, Romania.
Am J Case Rep. 2018 Jul 3;19:778-782. doi: 10.12659/AJCR.909240.
BACKGROUND Neuroendocrine tumors found in skin or soft tissues usually represent metastasis from other organs and are considered late manifestations of disease. Therefore, primary cutaneous and soft tissue neuroendocrine tumors are extremely rare. CASE REPORT We report a case of a 48-year-old male with a neuroendocrine tumor occurring in the subcutaneous abdominal fat, which had an echographic appearance of a vascular malformation. The finding was diagnosed as compatible with neuroendocrine tumor based on histopathological and immunohistochemical studies. No other sites of possible internal origin were detected on supplementary investigations. CONCLUSIONS Soft tissue neuroendocrine tumors may have an appearance on imaging studies that challenge physicians to make a correct diagnosis. Despite the rarity of these tumors, they should be included in the differential diagnosis of other soft tissue masses.
皮肤或软组织中发现的神经内分泌肿瘤通常代表其他器官的转移，被认为是疾病的晚期表现。因此，原发性皮肤和软组织神经内分泌肿瘤极为罕见。病例报告：我们报告一例48岁男性，其腹部皮下脂肪出现神经内分泌肿瘤，超声表现为血管畸形。基于组织病理学和免疫组织化学研究，该发现被诊断为与神经内分泌肿瘤相符。补充检查未发现其他可能的内部起源部位。结论：软组织神经内分泌肿瘤在影像学检查中可能有一些表现，给医生做出正确诊断带来挑战。尽管这些肿瘤罕见，但在其他软组织肿块的鉴别诊断中应考虑到它们。
