Computer tomography in cisternography with metrizamide.

The preliminary results with computer tomography in cisternography with metrizamide (Amipaque) indicates that both normal and abnormal cerebrospinal fluid dynamics can be accurately displayed with the advantage of spatial and quantitative detail. The pharmacokinetics of metrizamide clearance from cerebrospinal fluid to blood are similar to those of nuclides. Hence, similar problems in predicting response to ventricular shunting may arise. However, the quantitative features of this method have yet to be fully exploited.