Department of Geriatric Medicine, Marien Hospital Herne, Ruhr-Universität, Bochum, Germany.
Institute of Human Nutrition and Food Science, Christian-Albrechts-Universität, Kiel, Germany.
Eur J Clin Nutr. 2019 Apr;73(4):634-636. doi: 10.1038/s41430-018-0251-6. Epub 2018 Jul 2.
The relationship between hypophosphatemia (HP) and malnutrition in older hospitalized patients has received little attention. We sought to investigate this association among this population. The study participants were consecutively admitted to a geriatric acute care ward in six hospitals. Malnutrition screening was conducted by Mini Nutritional Assessment-Short Form. Patients were divided into two groups according to serum phosphate: HP (<0.68 mmol/l) and non-HP groups (>0.68 mmol/l). Of 335 participants, 7% of subjects had HP. Malnutrition or nutritional risk was present in 86 and 56% of participants with and without HP, respectively (P = 0.003). The analysis indicated 9.8, 86.4, 97.9 and 44.0% sensitivity, positive predictive value, specificity and negative predictive value of HP with regard to malnutrition, respectively. This study demonstrated that HP in older hospitalized patients is associated with malnutrition and may be used as an indicator of nutritional risk. Contrary, normal serum phosphate does not exclude being at nutritional risk.
低磷血症（HP）与老年住院患者营养不良之间的关系尚未得到充分关注。我们旨在对此人群进行相关研究。该研究纳入了六家医院老年急性护理病房的连续住院患者。采用微型营养评估-简短表格进行营养不良筛查。根据血清磷将患者分为两组：低磷血症组（<0.68mmol/l）和非低磷血症组（>0.68mmol/l）。335 名参与者中，7%的患者存在低磷血症。营养不良或营养风险分别存在于 86%和 56%的有和无低磷血症的患者中（P=0.003）。分析显示，低磷血症对营养不良的敏感性、阳性预测值、特异性和阴性预测值分别为 9.8%、86.4%、97.9%和 44.0%。本研究表明，老年住院患者的低磷血症与营养不良相关，可作为营养风险的指标。相反，血清磷正常并不能排除营养风险。
