Dent Elsa, Chapman Ian M, Piantadosi Cynthia, Visvanathan Renuka
University of Adelaide, South Australia, Discipline of Public Health, Level 7, 178 Frome Road, North Terrace Towers, Adelaide, South Australia, 5000.
Asia Pac J Clin Nutr. 2014;23(3):394-9. doi: 10.6133/apjcn.2014.23.3.18.
Malnutrition is a major problem in hospitalised older people. Many nutrition screening tools are available for malnutrition identification, however little is known about their prognostic ability. This prospective, observational study investigated the prognostic value of three nutritional screening tools in a Geriatric Evaluation and Management Unit: the Geriatric Nutritional Risk Index (GNRI), the Mini Nutritional Assessment (MNA) and the Mini Nutritional Assessment short form (MNA-SF), incorporating either body mass index or calf circumference. Poor six- month outcome was defined as new admission to higher level residential care or mortality at six months post-discharge. Predictive ability of poor outcome was assessed by logistic regression models, adjusting for age, gender, cognition and co-morbidity. Predictive accuracy was determined by area under Receiver Operator Characteristic curves, sensitivity, specificity, predictive values and Youden Index. One hundred and seventy-two consecutive patients with a mean (SD) age=85.2 (6.4) years were included in the study. Malnutrition was identified in 31% of patients using the MNA and was associated with a higher risk of poor six-month outcome when identified by the MNA (OR, 95% CI=3.29, 1.17-9.23) and the GNRI (OR, 95% CI=2.84, 1.31-6.19), but not by the MNA-SF. All screening tools lacked discriminative power for outcome prediction. The MNA and GNRI were useful clinical predictors of poor six-month outcome, although their accuracy of prediction was low. Nutritional screening remains a priority in the routine assessment of hospitalised older people.
营养不良是住院老年人面临的一个主要问题。有许多营养筛查工具可用于识别营养不良,但对其预后能力却知之甚少。这项前瞻性观察性研究调查了老年评估与管理病房中三种营养筛查工具的预后价值:老年营养风险指数(GNRI)、微型营养评定法(MNA)和微型营养评定法简表(MNA-SF),这些工具纳入了体重指数或小腿围度。不良的六个月结局定义为在出院后六个月入住更高水平的机构护理或死亡。通过逻辑回归模型评估不良结局的预测能力,并对年龄、性别、认知和合并症进行校正。通过受试者工作特征曲线下面积、敏感性、特异性、预测值和约登指数来确定预测准确性。该研究纳入了172例连续患者,平均(标准差)年龄为85.2(6.4)岁。使用MNA法在31%的患者中识别出营养不良,当通过MNA法(比值比,95%置信区间=3.29,1.17 - 9.23)和GNRI法(比值比,95%置信区间=2.84,1.31 - 6.19)识别出营养不良时,其与不良六个月结局的风险较高相关,但MNA-SF法未显示出这种相关性。所有筛查工具在结局预测方面均缺乏鉴别力。MNA法和GNRI法是不良六个月结局的有用临床预测指标,尽管它们的预测准确性较低。营养筛查在住院老年人的常规评估中仍然是一个优先事项。