Benedek Theodora, Dobreanu Dan
University of Medicine and Pharmacy of Tirgu Mures, 38 Gheorghe Marinescu street, Tirgu Mures, 540139, Romania.
J Crit Care Med (Targu Mures). 2015 Mar 1;1(1):5-10. doi: 10.1515/jccm-2015-0002. eCollection 2015 Jan.
Cardiogenic shock (CS) is a critical condition which often complicates the evolution of an acute myocardial infarction (AMI). At the same time, co-existence of chronic multi-vessel disease can lead to the development of cardiogenic shock in cases with pronounced haemodynamic instability. Different clinical studies have tried to identify the most appropriate treatment for critical cases of CS complicating AMI. This review aims to present the current status of recommended therapeutic strategies for severe cases of CS presenting as a complication of AMI, and try to shed light on the most appropriate therapeutic strategy as outlined in the current literature. The paper will discuss the different current strategies available for use in the treatment of this condition, includig interventional revascularisation, (complete or culprit), the role of new devices for providing mechanical circulatory support, and the potential role of new drug therapies and of hypothermia.
心源性休克（CS）是一种危急状况，常使急性心肌梗死（AMI）的病情复杂化。同时，慢性多支血管病变的并存可导致在血流动力学显著不稳定的情况下发生心源性休克。不同的临床研究试图确定针对并发AMI的CS危急病例的最恰当治疗方法。本综述旨在介绍作为AMI并发症出现的严重CS病例推荐治疗策略的现状，并尝试阐明当前文献中概述的最恰当治疗策略。本文将讨论目前可用于治疗这种病症的不同策略，包括介入性血运重建（完全或罪犯血管）、提供机械循环支持的新装置的作用，以及新药疗法和低温疗法的潜在作用。
