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猴子用甲泛葡胺脊髓造影后发生的蛛网膜炎。脑脊液中血液的影响。

Arachnoiditis following myelography with metrizamide in monkeys. Effect of blood in the cerebrospinal fluid.

作者信息

Haughton V M, Ho K C, Unger G F, Larson S J, Correa-Paz F

机构信息

Department of Radiology, Medical College of Wisconsin, Milwaukee County General Hospital 53226.

出版信息

Acta Radiol Suppl. 1977;355:373-8.

PMID:299682
Abstract

Monkeys were injected intrathecally with blood, metrizamide (Amipaque) or a mixture of blood and metrizamide. Twelve weeks later the animals were examined for evidence of arachnoiditis. Either blood or metrizamide alone in sufficient amounts resulted in arachnoiditis. The addition of blood to metrizamide did not alter the severity or risk of arachnoiditis from experimental myelography with metrizamide.

摘要

将血液、甲泛葡胺(阿米培克)或血液与甲泛葡胺的混合物鞘内注射给猴子。12周后检查动物是否有蛛网膜炎迹象。单独使用足够量的血液或甲泛葡胺均可导致蛛网膜炎。在甲泛葡胺实验性脊髓造影中,向甲泛葡胺中添加血液并未改变蛛网膜炎的严重程度或风险。

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