测量先兆子痫患者光电容积脉搏波的面积差比。
Measurement of area difference ratio of Photoplethysmographic pulse wave in patients with pre-eclampsia.
机构信息
Department of Anaesthesia, Women's Hospital, School of Medicine, Zhejiang University, Xueshi Rd 1, Hangzhou, 310006, China.
Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street, Boston, MA, 02111, USA.
出版信息
BMC Pregnancy Childbirth. 2018 Jul 3;18(1):280. doi: 10.1186/s12884-018-1914-y.
BACKGROUND
Preeclampsia (PE) is associated with an increase in maternal arterial stiffness, which may be reflected by photoplethysmography (PPG) of the pulse wave. The aim of this study was to investigate area difference ratio (ADR), a novel parameter derived from PPG, in women with and without preeclampsia.
METHODS
Patients with and without preeclampsia in the third trimester were enrolled. All patients had photoplethysmography of the pulse wave assessed. ADR was compared between the two groups.
RESULTS
Seventy-two patients in the third trimester of gestation, of which 36 had preeclampsia and 36 did not, were enrolled. The ADR was lower in the preeclampsia group vs. the non-preeclampsia group (0.725 [IQR 0.681-0.779] vs. 0.752 [IQR 0.717-0.910], P < 0.01).
CONCLUSIONS
Measuring the ADR through analyzing PPG of the pulse wave may be a useful diagnostic tool in patients with preeclampsia.
背景
子痫前期（PE）与母体动脉僵硬度增加有关，这可能反映在脉搏波光体积描记图（PPG）上。本研究旨在探讨源自 PPG 的新型参数——面积差异比（ADR）在子痫前期患者中的应用。
方法
纳入了处于妊娠晚期且患有或不患有子痫前期的患者。所有患者均进行了脉搏波 PPG 评估。比较了两组之间的 ADR。
结果
共纳入 72 例妊娠晚期患者，其中 36 例患有子痫前期，36 例未患有子痫前期。子痫前期组的 ADR 低于非子痫前期组（0.725 [IQR 0.681-0.779] vs. 0.752 [IQR 0.717-0.910]，P < 0.01）。
结论
通过分析脉搏波 PPG 测量 ADR 可能是子痫前期患者的一种有用的诊断工具。
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