体外冲击波疗法治疗股骨头坏死的潜在作用的荟萃分析。
Meta-analysis of the potential role of extracorporeal shockwave therapy in osteonecrosis of the femoral head.
机构信息
Department of Osteonecrosis and Joint Reconstruction, Honghui Hospital Xi'an Jiao Tong University Health Science Center, No. 555 Youyi East Road, Xi'an, Shaanxi, 710054, People's Republic of China.
Shaanxi University of Chinese Medicine, Shiji Ave, New Economic Zone, Xi'an-Xianyang, Shaanxi, 712046, People's Republic of China.
出版信息
J Orthop Surg Res. 2018 Jul 3;13(1):166. doi: 10.1186/s13018-018-0861-7.
BACKGROUND
We aimed to evaluate the role of extracorporeal shockwave therapy (ESWT) in improving osteonecrosis of the femoral head (ONFH).
METHODS
We searched studies focusing on the role of ESWT in ONFH using PubMed, Embase, the Cochrane Library, WanFang, VIP, and CNKI databases updated up to July 28, 2017, without language restriction. Standardized mean difference (SMD) values and 95% confidence intervals (95% CIs) were pooled to compare the pain score and Harris hip score for ESWT treatment and other treatment strategies.
RESULTS
Four articles, including 230 ONFH patients, were eligible for the meta-analysis. No significant differences were found in the pain score (SMD = - 1.0104; 95% CI - 2.3279-0.3071) and Harris hip score (SMD = 0.3717; 95% CI - 0.3125-1.0559) between the two groups before treatment. After treatment, significant differences were found between the experimental and control groups in the pain score (SMD = - 2.1148; 95% CI - 3.2332-0.9965) and Harris hip score (SMD = 2.1377; 95% CI 1.2875-2.9880). There were no significant differences in pain score before and after treatment between the two groups (SMD = - 0.7353; 95% CI - 2.1272-0.6566), but significant differences were found in the Harris hip score (SMD = 1.2969; 95% CI 0.7171-1.8767).
CONCLUSION
For patients at an early stage, ESWT may be safe and effective for relief of pain and improvement of motor function.
背景
我们旨在评估体外冲击波疗法（ESWT）在改善股骨头坏死（ONFH）中的作用。
方法
我们使用 PubMed、Embase、Cochrane 图书馆、万方、维普及中国知网数据库检索了截止 2017 年 7 月 28 日所有关于 ESWT 在 ONFH 中作用的研究，不限制语言。采用标准化均数差（SMD）值及其 95%置信区间（95%CI）来比较 ESWT 治疗与其他治疗策略的疼痛评分和 Harris 髋关节评分。
结果
四项研究，共纳入 230 例 ONFH 患者，符合纳入标准进行荟萃分析。治疗前两组疼痛评分（SMD=-1.0104；95%CI-2.3279-0.3071）和 Harris 髋关节评分（SMD=0.3717；95%CI-0.3125-1.0559）差异无统计学意义。治疗后，实验组与对照组在疼痛评分（SMD=-2.1148；95%CI-3.2332-0.9965）和 Harris 髋关节评分（SMD=2.1377；95%CI 1.2875-2.9880）方面差异有统计学意义。两组治疗前后疼痛评分差异无统计学意义（SMD=-0.7353；95%CI-2.1272-0.6566），但 Harris 髋关节评分差异有统计学意义（SMD=1.2969；95%CI 0.7171-1.8767）。
结论
对于早期患者，ESWT 可能是一种安全有效的缓解疼痛和改善运动功能的方法。
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