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成年人群中癌症与精神障碍的时间顺序。

Temporal order of cancers and mental disorders in an adult population.

作者信息

Cawthorpe David, Kerba Marc, Narendran Aru, Ghuttora Harleen, Chartier Gabrielle, Sartorius Norman

机构信息

Faculty of Medicine, Departments of Psychiatry & Community Health Sciences, Institute for Child and Maternal Health, University of Calgary, Alberta, Canada.

Department of Oncology, University of Calgary, Alberta, Canada.

出版信息

BJPsych Open. 2018 Apr 19;4(3):95-105. doi: 10.1192/bjo.2018.5. eCollection 2018 May.

DOI:10.1192/bjo.2018.5
PMID:29971152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6020283/
Abstract

BACKGROUND

Population-based examination of comorbidity is an emerging field of study.

AIMS

The purpose of the present population level study is to expand our understanding of how cancer and mental illness are temporally associated.

METHOD

A sample of 83 648 056 physician billing records for 664 838 (56% female) unique individuals over the age of 18 was stratified on ages 19-49 years and 50+ years, with temporal order of mental disorder and cancer forming the basis of comparison.

RESULTS

Mental disorders preceded cancers for both genders within each age strata. The full range of cancers and mental disorders preceding or following each pivot ICD class are described in terms of frequency of diagnosis and duration in days, with specific examples illustrated.

CONCLUSIONS

The temporal comorbidity between specific cancers and mental disorders may be useful in screening or clinical planning and may represent indicators of disease mechanism that warrant further screening or investigation.

DECLARATION OF INTEREST

None.

摘要

背景

基于人群的共病研究是一个新兴的研究领域。

目的

本人群水平研究的目的是加深我们对癌症与精神疾病在时间上如何关联的理解。

方法

对18岁以上664838名(56%为女性)个体的83648056份医生计费记录样本按19至49岁和50岁及以上进行分层,以精神障碍和癌症的时间顺序作为比较基础。

结果

在每个年龄层中,两种性别的精神障碍均先于癌症出现。根据诊断频率和天数描述了每个关键国际疾病分类类别之前或之后的所有癌症和精神障碍,并给出了具体示例。

结论

特定癌症与精神障碍之间的时间共病情况可能有助于筛查或临床规划,并且可能代表疾病机制的指标,值得进一步筛查或调查。

利益声明

无。

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