Mo Wenquan, Pei Jian, Wang Jie, Chu Wenhao, Liu Meng, Li Honghong, Chen Shenxu, Lu Zhou, Zhang Ping, Yang Hui
Department of Acupuncture and Moxibustion, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.
Department of Acupuncture and Moxibustion, Longhua Hospital Affiliated to Shanghai University of TCM; 3Department of Otolaryngology, Huadong Hospital Affiliated to Fudan University.
Zhongguo Zhen Jiu. 2018 Jun 12;38(6):604-8. doi: 10.13703/j.0255-2930.2018.06.009.
To observe the effect differences among the comprehensive therapy, acupuncture and oral mecobalamine for senile sensorineural hearing loss.
A total of 126 senile sensorineural hearing loss patients were randomized into a comprehensive group, an acupuncture group and a western medication group, 42 cases in each group. After removing and discontinuing cases, 40 cases in each group were included in the analysis. Acupuncture, acupoint injection and auricular point pressing were used in the comprehensive group. Acupuncture for 2 courses was at the affected Tinggong (SI 19), Tinghui (GB 2), Yifeng (TE 17), etc, once every other day, 10 times as a course with one week rest between 2 courses, 3 times a week. Acupuncture as the comprehensive group was applied in the acupuncture group. Mecobalamin tablet was prescribed orally for 2 courses in the western medication group, 3 times a day, 0.5 mg a time, 3 weeks as a course, one week at the interval. Pure tone hearing threshold value and tinnitus grading were observed before and after intervention in the three groups. The clinical effects were compared.
After treatment, pure tone hearing threshold value and tinnitus grading were better than those before treatment in the three groups (all <0.05), with better results in the comprehensive group than those in the other two groups (all <0.05). The total effective rate of pure tone hearing threshold value was 82.5% (33/40) in the comprehensive group, which was superior to 67.0% (27/40) in the acupuncture group and 62.5% (25/40) in the western medication group (both <0.05). The total effective rate of tinnitus was 83.3% (30/36) in the comprehensive group, which was superior to 69.7% (23/33) in the acupuncture group and 57.1% (20/35) in the western medication group (both <0.05).
The clinical effects of comprehensive therapy on senile sensorineural hearing loss are superior to those of simple acupuncture and oral administration of mecobalamin in terms of pure tone hearing threshold value and tinnitus grading.
观察综合疗法、针刺疗法及口服甲钴胺治疗老年感音神经性听力损失的疗效差异。
将126例老年感音神经性听力损失患者随机分为综合组、针刺组和西药组，每组42例。剔除和脱落病例后，每组纳入40例进行分析。综合组采用针刺、穴位注射及耳穴贴压治疗。针刺选取患侧听宫（SI 19）、听会（GB 2）、翳风（TE 17）等穴位，针刺2个疗程，隔日1次，每周3次，每次10次为1个疗程，2个疗程之间休息1周。针刺组针刺方法同综合组。西药组口服甲钴胺片，2个疗程，每日3次，每次0.5 mg，3周为1个疗程，疗程间隔1周。观察三组干预前后的纯音听阈值及耳鸣分级情况，并比较临床疗效。
治疗后，三组的纯音听阈值及耳鸣分级均优于治疗前（均P<0.05），综合组效果优于其他两组（均P<0.05）。综合组纯音听阈值总有效率为82.5%（33/40），优于针刺组的67.0%（27/40）和西药组的62.5%（25/40）（均P<0.05）。综合组耳鸣总有效率为83.3%（30/36），优于针刺组的69.7%（23/33）和西药组的57.1%（20/35）（均P<0.05）。
在纯音听阈值及耳鸣分级方面，综合疗法治疗老年感音神经性听力损失的临床疗效优于单纯针刺及口服甲钴胺。
