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针刺联合口服西药治疗梅尼埃病:一项随机对照试验

[Acupuncture combined with oral western medication for Meniere's disease: a randomized controlled trial].

作者信息

Wu Dong, Liu Bo, Wang Hongcai, Rong Peijing, Chen Luquan, Duan Jinping, Chen Chao, Zhai Xu

机构信息

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China; Department of Traditional Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing 100730.

Beijing Institute of Otolaryngology.

出版信息

Zhongguo Zhen Jiu. 2018 Oct 12;38(10):1047-52. doi: 10.13703/j.0255-2930.2018.10.005.

DOI:10.13703/j.0255-2930.2018.10.005
PMID:30672233
Abstract

OBJECTIVE

To compare the effect difference between acupuncture combined with western medication and simple western medication for Meniere's disease.

METHODS

Ninety-six patients with Meniere's disease were randomly assigned into a combination group (48 cases, 12 cases dropping) and a medication group (48 cases, 9 cases dropping). Betastatin mesylate tablets (once 12 mg, 3 times a day) and mecobalamin tablets (once 0.5 mg, 3 times a day) were prescribed orally in the two groups. Acupuncture was used in the combination group, twice a week, 20 min a time, and the acupoints were Baihui (GV 20), Fengchi (GB 20), Tinggong (SI 19), Hegu (LI 4), Quchi (LI 11), Zusanli (ST 36), Fenglong (ST 40), Taichong (LR 3), Taixi (KI 3) and Tianshu (ST 25). All the treatment was given for continuous 12 weeks. The symptoms were observed by dizziness handicap inventory (DHI), tinnitus handicap inventory (THI), pure tone audiometry score and stuffy ear visual analogue scale (VAS). The effects were compared in the aspects of dizziness, hearing and activity.

RESULTS

The scores of DHI, THI, pure tone audiometry and VAS scores after treatment were lower than those before treatment in the two groups (all <0.05), with lower scores of the above 4 indexes in the combination group after treatment (all <0.05). The difference values before and after treatment of the 4 indexes in the combination group were higher than those in the medication group (all <0.05). The effective rates of dizziness, hearing and activity in the combination group were 97.2% (35/36), 91.7% (33/36), 88.9% (32/36), which were better than 71.8% (28/39), 74.4% (29/39) and 69.2% (27/39) in the medication group (all <0.05).

CONCLUSION

Acupuncture combined with conventional medication achieve better effect than simple conventional medication.

摘要

目的

比较针刺联合西药与单纯西药治疗梅尼埃病的疗效差异。

方法

将96例梅尼埃病患者随机分为联合组(48例,脱落12例)和药物组(48例,脱落9例)。两组均口服甲磺酸倍他司汀片(一次12 mg,一日3次)和甲钴胺片(一次0.5 mg,一日3次)。联合组采用针刺治疗,每周2次,每次20分钟,穴位选取百会(GV 20)、风池(GB 20)、听宫(SI 19)、合谷(LI 4)、曲池(LI 11)、足三里(ST 36)、丰隆(ST 40)、太冲(LR 3)、太溪(KI 3)、天枢(ST 25)。所有治疗持续12周。采用头晕残障量表(DHI)、耳鸣残障量表(THI)、纯音听力计评分及耳闷视觉模拟量表(VAS)观察症状。比较两组在头晕、听力和活动方面的疗效。

结果

两组治疗后DHI、THI、纯音听力计及VAS评分均低于治疗前(均P<0.05),联合组治疗后上述4项指标评分更低(均P<0.05)。联合组4项指标治疗前后差值高于药物组(均P<0.05)。联合组头晕、听力及活动有效率分别为97.2%(35/36)、91.7%(33/36)、88.9%(32/36),优于药物组的71.8%(28/39)、74.4%(29/39)、69.2%(27/39)(均P<0.05)。

结论

针刺联合常规药物治疗梅尼埃病的效果优于单纯常规药物治疗。

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