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[用于牙周再生的生物诱导性生物材料]

[Bioinductive biomaterials for periodontal regeneration].

作者信息

Zhang Y F

机构信息

The State Key Laboratory Breeding Base of Basic Science of Stomatology & Key Laboratory of Oral Biomedicine Ministry of Education, School of Stomatology, Wuhan University, Wuhan 430079, China.

出版信息

Zhonghua Kou Qiang Yi Xue Za Zhi. 2017 Oct 9;52(10):615-619. doi: 10.3760/cma.j.issn.1002-0098.2017.10.007.

Abstract

Periodontal regeneration is a great challenge faced by clinical treatment, and traditional therapies are not effective in regenerating periodontal tissues. Bioinductive biomaterials are materials that are able to induce the regeneration of damaged tissues, and they can induce the migration of stem cells or precursor cells to the defect site to proliferate, differentiate for tissue regeneration. For example, the osteoinductive biomaterials are able to induce regeneration of alveolar bone. In this review, the writer combined the recent advances of both clinical and scientific field, and summarize the application of bioinductive biomaterials includingautogenous bone, human derived growth factors, enamel matrix proteins and platelet-rich fibrin.

摘要

牙周组织再生是临床治疗面临的巨大挑战,传统疗法在牙周组织再生方面效果不佳。生物诱导性生物材料是能够诱导受损组织再生的材料,它们可以诱导干细胞或前体细胞迁移至缺损部位进行增殖、分化以实现组织再生。例如,骨诱导性生物材料能够诱导牙槽骨再生。在本综述中,作者结合了临床和科学领域的最新进展,总结了生物诱导性生物材料的应用,包括自体骨、人源生长因子、釉基质蛋白和富血小板纤维蛋白。

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