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医院手术量对经皮外周血管斑块旋切术结局的影响——来自全国住院患者样本的观察性分析

Effect of hospital volume on outcomes of percutaneous peripheral atherectomy - An observational analysis from National Inpatient Sample.

作者信息

Patel Samir V, Sonani Rajesh, Patel Palak, Patel Mihir, Bhatt Parth, Badheka Apurva

机构信息

1 Sparks Regional Medical Center, University of Arkansas Medical Sciences west, Fort Smith, AR, USA.

2 Brandon Regional Hospital, Brandon, FL, USA.

出版信息

Vascular. 2018 Dec;26(6):615-625. doi: 10.1177/1708538118786596. Epub 2018 Jul 4.

Abstract

BACKGROUND

Although the published literature has reported an inverse association between hospital volume and outcomes of coronary interventions, sparse data are available for percutaneous peripheral atherectomy (PPA). The aim of our study was to examine the effect of hospital volume on outcomes of PPA.

METHODS

Using the Nationwide Inpatient Sample (NIS) database of the year 2012, PPA with ICD-9 code of 17.56 was identified. The primary outcomes were mortality and amputation rates; secondary outcomes were peri-procedural complications, cost, and length of hospitalization and discharge disposition of the patient. Multivariate models were generated for predictors of the outcomes.

RESULTS

We identified a total of 21,015 patients with mean age of 69.53 years, with 56% males. Higher hospital volume centers were associated with a significantly lower mortality (OR 0.42, 95% CI 0.30-0.57, p < 0.0001), amputation rates (5.34% vs. 9.32%, p < 0.0001), combined endpoint of mortality and complications (OR 0.53, 95% CI 0.49-0.58, p < 0.0001), shorter length of hospital stay (LOS) (4.86 vs. 6.79 days, p < 0.0001) and lower hospitalization cost ($23,062 vs. $30,794, p < 0.0001). Subgroup analysis for acute and chronic limb ischemia showed similar results.

CONCLUSION

Hospital procedure volume is an independent predictor of mortality, amputation rates, complications, LOS, and costs in patients undergoing PPA with an inverse relationship.

摘要

背景

尽管已发表的文献报道了医院手术量与冠状动脉介入治疗结果之间存在负相关,但关于经皮外周血管旋切术(PPA)的数据却很少。我们研究的目的是探讨医院手术量对PPA治疗结果的影响。

方法

利用2012年全国住院患者样本(NIS)数据库,确定国际疾病分类第九版(ICD-9)编码为17.56的PPA病例。主要结局指标为死亡率和截肢率;次要结局指标为围手术期并发症、费用、住院时间以及患者出院处置情况。针对这些结局指标的预测因素建立多变量模型。

结果

我们共纳入21015例患者,平均年龄69.53岁,其中56%为男性。手术量较高的医院中心患者死亡率显著较低(比值比[OR]0.42,95%置信区间[CI]0.30 - 0.57,p < 0.0001),截肢率较低(5.34%对9.32%,p < 0.0001),死亡率和并发症的联合终点较低(OR 0.53,95% CI 0.49 - 0.58,p < 0.0001),住院时间较短(4.86天对6.79天,p < 0.0001),住院费用较低(23062美元对30794美元,p < 0.0001)。急性和慢性肢体缺血的亚组分析显示了类似结果。

结论

医院手术量是接受PPA治疗患者死亡率、截肢率、并发症、住院时间和费用的独立预测因素,且呈负相关。

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