通过仙台病毒诱导在人外周血白细胞中产生的酸不稳定干扰素。
Acid-labile interferon produced in human peripheral leukocytes by induction with Sendai virus.
作者信息
Matsuoka H, Kakui Y, Tanaka A, Cho Y, Imanishi J
出版信息
J Gen Virol. 1985 Nov;66 ( Pt 11):2491-4. doi: 10.1099/0022-1317-66-11-2491.
PMID:2997378
Abstract
An acid-labile interferon-alpha (IFN-alpha) exists in IFN produced in human peripheral leukocytes with Sendai virus. This activity was found in fractions of molecular weights about 100 000 (100K), 58K and 44K. The IFN activity in the 100K fraction was neutralized with anti-HuIFN-alpha serum alone, but activity in the 58K and 44K fractions was neutralized only by a mixture of anti-HuIFN-alpha and anti-HuIFN-beta sera.
摘要
一种酸不稳定的α干扰素（IFN-α）存在于经仙台病毒处理的人外周血白细胞产生的干扰素中。这种活性在分子量约为100000（100K）、58K和44K的组分中被发现。100K组分中的IFN活性仅用抗HuIFN-α血清即可中和，但58K和44K组分中的活性仅被抗HuIFN-α和抗HuIFN-β血清的混合物中和。
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