利用特异性单克隆抗体研究的一种分子量为28000的人巨细胞病毒结构多肽。
A 28000 molecular weight human cytomegalovirus structural polypeptide studied by means of a specific monoclonal antibody.
作者信息
Re M C, Landini M P, Coppolecchia P, Furlini G, La Placa M
出版信息
J Gen Virol. 1985 Nov;66 ( Pt 11):2507-11. doi: 10.1099/0022-1317-66-11-2507.
PMID:2997381
Abstract
We have produced a monoclonal antibody against human cytomegalovirus (HCMV) which recognizes a structural protein of 28 000 mol. wt. which is present in both the cytoplasm of infected cells during the late phase of the viral replication cycle and in the extracellular viral particles. This antigen was detected in all HCMV strains assayed and reacted with human sera having anti-HCMV antibodies.
摘要
我们制备了一种针对人巨细胞病毒（HCMV）的单克隆抗体，该抗体可识别一种分子量为28000道尔顿的结构蛋白，这种蛋白在病毒复制周期后期存在于被感染细胞的细胞质中以及细胞外病毒颗粒中。在所有检测的HCMV毒株中均检测到了这种抗原，并且它能与具有抗HCMV抗体的人血清发生反应。
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