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心律失常患者两晚动态睡眠测试的比较

A Comparison of Two Nights of Ambulatory Sleep Testing in Arrhythmia Patients.

作者信息

Abumuamar Asmaa M, Dorian Paul, Newman David, Shapiro Colin M

机构信息

Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

Department of Cardiology, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.

出版信息

Sleep Disord. 2018 Jun 3;2018:2394146. doi: 10.1155/2018/2394146. eCollection 2018.

Abstract

INTRODUCTION

Obstructive sleep apnea (OSA) is common and usually underdetected in patients with cardiac arrhythmia. Ambulatory sleep testing may provide an alternative method for detection of OSA under realistic conditions compared to in-laboratory polysomnography. We aimed to (1) determine the sleep architecture in arrhythmia patients; (2) detect differences in sleep parameters between patients with and without OSA; and (3) compare the results of two consecutive nights of unattended ambulatory sleep testing.

METHODS

Consecutive patients with unknown OSA status were recruited from arrhythmia clinics. Patients underwent two consecutive nights of self-applied in-home sleep testing replete with electroencephalogram (EEG) recording.

RESULTS

One hundred patients were recruited. The mean age was 64 ± 13 years (70% males). OSA (AHI ≥ 5/h) was detected in 85% of patients. In the total sample, the sleep efficiency was reduced, and sleep onset latency was longer compared to a reference population of the same age. In patients with OSA, the sleep efficiency and the percentage of slow wave sleep were reduced; however, the arousal and periodic limb movement indices were increased compared to patients without OSA. The two nights of the ambulatory sleep testing showed consistent results with an excellent test-retest reliability for the AHI (ICC = 0.813). REM latency was shorter during the second night of sleep recording ( = 0.02). There were no other significant differences in the sleep architecture, respiratory indices, and other sleep parameters between the first and the second night of the ambulatory sleep recording.

CONCLUSIONS

There is no significant difference in the respiratory parameters obtained during two consecutive nights of ambulatory sleep testing. Ambulatory studies incorporating EEG may provide a reliable, convenient, and economically efficient method for sleep assessment and there appears to be no significant night-to-night variability.

摘要

引言

阻塞性睡眠呼吸暂停(OSA)很常见,在心律失常患者中通常未被充分检测到。与实验室多导睡眠图相比,动态睡眠测试可能为在实际情况下检测OSA提供一种替代方法。我们旨在:(1)确定心律失常患者的睡眠结构;(2)检测有和没有OSA的患者之间睡眠参数的差异;(3)比较连续两晚无人值守的动态睡眠测试结果。

方法

从心律失常诊所招募连续的OSA状态未知的患者。患者连续两晚在家自行进行睡眠测试,并进行脑电图(EEG)记录。

结果

共招募了100名患者。平均年龄为64±13岁(70%为男性)。85%的患者检测到OSA(呼吸暂停低通气指数≥5次/小时)。在整个样本中,与同年龄的参考人群相比,睡眠效率降低,入睡潜伏期延长。在患有OSA的患者中,睡眠效率和慢波睡眠百分比降低;然而,与没有OSA的患者相比,觉醒和周期性肢体运动指数增加。动态睡眠测试的两晚结果一致,呼吸暂停低通气指数的重测信度极佳(组内相关系数=0.813)。在睡眠记录的第二晚,快速眼动潜伏期较短(P=0.02)。动态睡眠记录的第一晚和第二晚之间,在睡眠结构、呼吸指数和其他睡眠参数方面没有其他显著差异。

结论

连续两晚的动态睡眠测试所获得的呼吸参数没有显著差异。纳入脑电图的动态研究可能为睡眠评估提供一种可靠、方便且经济高效的方法,并且似乎没有显著的夜间变异性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/852e/6008611/3e9279430a2b/SD2018-2394146.001.jpg

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