Bristol Urological Institute, Southmead Hospital, Bristol, UK.
School of Physiology, Pharmacology, and Neuroscience, University of Bristol, Bristol, UK.
Neurourol Urodyn. 2018 Nov;37(8):2745-2752. doi: 10.1002/nau.23745. Epub 2018 Jul 4.
To test the significance of association between a validated index of detrusor contractility, v , the Watts Factor, and the Detrusor Contractility Parameter, t ; and to test whether t depends on outflow tract resistance as indicated by Bladder Outlet Obstruction Index (BOOI).
Thirty-seven pressure-flow traces from 20 male and 17 female patients were analyzed and forms of the Watts Factor, t and BOOI were compared with v .
The Detrusor Contractility Parameter, t , is significantly associated with v for both women and men without a high degree of bladder outlet obstruction. The Watts Factor only had a significant association with v at the point of maximum flow in women.
The Detrusor Contractility Parameter (DCP) (t ), can be measured easily from the pressure flow curves of a urodynamic test. The Watts Factor at maximum urine flow, WF , can be readily calculated, but is only applicable to women. In both women and men without a high degree of bladder outlet obstruction, DCP is better associated with true detrusor contractility than any Watts Factor analysis.
检验逼尿肌收缩性的验证指数 v、沃茨因子(Watts Factor)和逼尿肌收缩参数 t 之间的关联的显著性,并检验 t 是否取决于膀胱出口梗阻指数(Bladder Outlet Obstruction Index,BOOI)所表示的流出道阻力。
分析了 20 名男性和 17 名女性患者的 37 条压力-流量曲线,并对沃茨因子 t 和 BOOI 与 v 进行了比较。
在没有高度膀胱出口梗阻的情况下,逼尿肌收缩参数 t 与 v 对男性和女性均有显著的相关性。沃茨因子仅在女性最大尿流时与 v 有显著相关性。
逼尿肌收缩参数(DCP)(t)可以从尿动力学测试的压力-流量曲线中轻松测量。在没有高度膀胱出口梗阻的男性和女性中,DCP 与真正的逼尿肌收缩性的相关性优于任何沃茨因子分析。